Measuring Exercise-Induced Secreted Protein Acidic and Rich in Cysteine Expression as a Molecular Tool to Optimize Personalized Medicine

The numerous exercise benefits for health as well as applications for diseases has lead to exercise being prescribed in many pathological conditions. Secreted protein acidic and rich in cysteine (SPARC) gene expression is stimulated by exercise and SPARC has been suggested as a molecular mediator of...

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Autores principales:	Abdelaziz Ghanemi, Mayumi Yoshioka, Jonny St-Amand
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	exercise secreted protein acidic and rich in cysteine expression medicine Genetics QH426-470
Acceso en línea:	https://doaj.org/article/4e06b2a3e271461cafb144cab4b549fc
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spelling	oai:doaj.org-article:4e06b2a3e271461cafb144cab4b549fc2021-11-25T17:42:31ZMeasuring Exercise-Induced Secreted Protein Acidic and Rich in Cysteine Expression as a Molecular Tool to Optimize Personalized Medicine10.3390/genes121118322073-4425https://doaj.org/article/4e06b2a3e271461cafb144cab4b549fc2021-11-01T00:00:00Zhttps://www.mdpi.com/2073-4425/12/11/1832https://doaj.org/toc/2073-4425The numerous exercise benefits for health as well as applications for diseases has lead to exercise being prescribed in many pathological conditions. Secreted protein acidic and rich in cysteine (SPARC) gene expression is stimulated by exercise and SPARC has been suggested as a molecular mediator of exercise. Therefore, we suggest using this property for personalized medicine. This can be achieved by prescribing the exercise with a pattern (duration, intensity, etc.) that corresponds to the optimum <i>SPARC/Sparc</i> expression. We expect this approach to optimize the exercise therapy in both the preventive and curative contexts. In the research field, measuring exercise -dependent expression of <i>Sparc</i> would represent a molecular tool to further optimize the selection of exercise animal models as well.Abdelaziz GhanemiMayumi YoshiokaJonny St-AmandMDPI AGarticleexercisesecreted protein acidic and rich in cysteineexpressionmedicineGeneticsQH426-470ENGenes, Vol 12, Iss 1832, p 1832 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	exercise secreted protein acidic and rich in cysteine expression medicine Genetics QH426-470
spellingShingle	exercise secreted protein acidic and rich in cysteine expression medicine Genetics QH426-470 Abdelaziz Ghanemi Mayumi Yoshioka Jonny St-Amand Measuring Exercise-Induced Secreted Protein Acidic and Rich in Cysteine Expression as a Molecular Tool to Optimize Personalized Medicine
description	The numerous exercise benefits for health as well as applications for diseases has lead to exercise being prescribed in many pathological conditions. Secreted protein acidic and rich in cysteine (SPARC) gene expression is stimulated by exercise and SPARC has been suggested as a molecular mediator of exercise. Therefore, we suggest using this property for personalized medicine. This can be achieved by prescribing the exercise with a pattern (duration, intensity, etc.) that corresponds to the optimum <i>SPARC/Sparc</i> expression. We expect this approach to optimize the exercise therapy in both the preventive and curative contexts. In the research field, measuring exercise -dependent expression of <i>Sparc</i> would represent a molecular tool to further optimize the selection of exercise animal models as well.
format	article
author	Abdelaziz Ghanemi Mayumi Yoshioka Jonny St-Amand
author_facet	Abdelaziz Ghanemi Mayumi Yoshioka Jonny St-Amand
author_sort	Abdelaziz Ghanemi
title	Measuring Exercise-Induced Secreted Protein Acidic and Rich in Cysteine Expression as a Molecular Tool to Optimize Personalized Medicine
title_short	Measuring Exercise-Induced Secreted Protein Acidic and Rich in Cysteine Expression as a Molecular Tool to Optimize Personalized Medicine
title_full	Measuring Exercise-Induced Secreted Protein Acidic and Rich in Cysteine Expression as a Molecular Tool to Optimize Personalized Medicine
title_fullStr	Measuring Exercise-Induced Secreted Protein Acidic and Rich in Cysteine Expression as a Molecular Tool to Optimize Personalized Medicine
title_full_unstemmed	Measuring Exercise-Induced Secreted Protein Acidic and Rich in Cysteine Expression as a Molecular Tool to Optimize Personalized Medicine
title_sort	measuring exercise-induced secreted protein acidic and rich in cysteine expression as a molecular tool to optimize personalized medicine
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/4e06b2a3e271461cafb144cab4b549fc
work_keys_str_mv	AT abdelazizghanemi measuringexerciseinducedsecretedproteinacidicandrichincysteineexpressionasamoleculartooltooptimizepersonalizedmedicine AT mayumiyoshioka measuringexerciseinducedsecretedproteinacidicandrichincysteineexpressionasamoleculartooltooptimizepersonalizedmedicine AT jonnystamand measuringexerciseinducedsecretedproteinacidicandrichincysteineexpressionasamoleculartooltooptimizepersonalizedmedicine
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Measuring Exercise-Induced Secreted Protein Acidic and Rich in Cysteine Expression as a Molecular Tool to Optimize Personalized Medicine

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