BABEL: using deep learning to translate between single-cell datasets
Recent advances in sequencing and barcoding technologies have enabled researchers to simultaneously profile gene expression, chromatin accessibility, and/or protein levels in single cells. However, these multiomic techniques often pose technical and financial barriers that limit their practicality....
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Nature Portfolio
2021
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oai:doaj.org-article:4e0b2ba8f4ed4bae8a12fec4eec6f3c52021-12-02T15:55:21ZBABEL: using deep learning to translate between single-cell datasets10.1038/s42003-021-02135-92399-3642https://doaj.org/article/4e0b2ba8f4ed4bae8a12fec4eec6f3c52021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02135-9https://doaj.org/toc/2399-3642Recent advances in sequencing and barcoding technologies have enabled researchers to simultaneously profile gene expression, chromatin accessibility, and/or protein levels in single cells. However, these multiomic techniques often pose technical and financial barriers that limit their practicality. Kevin Wu and colleagues recently developed BABEL, a deep learning algorithm that can effectively translate between transcriptomic and chromatin profiles in single cells, thereby enabling researchers to perform multiomic analyses from an individual dataset.George Andrew S. InglisNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-1 (2021) |
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Biology (General) QH301-705.5 George Andrew S. Inglis BABEL: using deep learning to translate between single-cell datasets |
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Recent advances in sequencing and barcoding technologies have enabled researchers to simultaneously profile gene expression, chromatin accessibility, and/or protein levels in single cells. However, these multiomic techniques often pose technical and financial barriers that limit their practicality. Kevin Wu and colleagues recently developed BABEL, a deep learning algorithm that can effectively translate between transcriptomic and chromatin profiles in single cells, thereby enabling researchers to perform multiomic analyses from an individual dataset. |
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article |
author |
George Andrew S. Inglis |
author_facet |
George Andrew S. Inglis |
author_sort |
George Andrew S. Inglis |
title |
BABEL: using deep learning to translate between single-cell datasets |
title_short |
BABEL: using deep learning to translate between single-cell datasets |
title_full |
BABEL: using deep learning to translate between single-cell datasets |
title_fullStr |
BABEL: using deep learning to translate between single-cell datasets |
title_full_unstemmed |
BABEL: using deep learning to translate between single-cell datasets |
title_sort |
babel: using deep learning to translate between single-cell datasets |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/4e0b2ba8f4ed4bae8a12fec4eec6f3c5 |
work_keys_str_mv |
AT georgeandrewsinglis babelusingdeeplearningtotranslatebetweensinglecelldatasets |
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1718385390047461376 |