BABEL: using deep learning to translate between single-cell datasets

Recent advances in sequencing and barcoding technologies have enabled researchers to simultaneously profile gene expression, chromatin accessibility, and/or protein levels in single cells. However, these multiomic techniques often pose technical and financial barriers that limit their practicality....

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Autor principal: George Andrew S. Inglis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4e0b2ba8f4ed4bae8a12fec4eec6f3c5
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spelling oai:doaj.org-article:4e0b2ba8f4ed4bae8a12fec4eec6f3c52021-12-02T15:55:21ZBABEL: using deep learning to translate between single-cell datasets10.1038/s42003-021-02135-92399-3642https://doaj.org/article/4e0b2ba8f4ed4bae8a12fec4eec6f3c52021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02135-9https://doaj.org/toc/2399-3642Recent advances in sequencing and barcoding technologies have enabled researchers to simultaneously profile gene expression, chromatin accessibility, and/or protein levels in single cells. However, these multiomic techniques often pose technical and financial barriers that limit their practicality. Kevin Wu and colleagues recently developed BABEL, a deep learning algorithm that can effectively translate between transcriptomic and chromatin profiles in single cells, thereby enabling researchers to perform multiomic analyses from an individual dataset.George Andrew S. InglisNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
George Andrew S. Inglis
BABEL: using deep learning to translate between single-cell datasets
description Recent advances in sequencing and barcoding technologies have enabled researchers to simultaneously profile gene expression, chromatin accessibility, and/or protein levels in single cells. However, these multiomic techniques often pose technical and financial barriers that limit their practicality. Kevin Wu and colleagues recently developed BABEL, a deep learning algorithm that can effectively translate between transcriptomic and chromatin profiles in single cells, thereby enabling researchers to perform multiomic analyses from an individual dataset.
format article
author George Andrew S. Inglis
author_facet George Andrew S. Inglis
author_sort George Andrew S. Inglis
title BABEL: using deep learning to translate between single-cell datasets
title_short BABEL: using deep learning to translate between single-cell datasets
title_full BABEL: using deep learning to translate between single-cell datasets
title_fullStr BABEL: using deep learning to translate between single-cell datasets
title_full_unstemmed BABEL: using deep learning to translate between single-cell datasets
title_sort babel: using deep learning to translate between single-cell datasets
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4e0b2ba8f4ed4bae8a12fec4eec6f3c5
work_keys_str_mv AT georgeandrewsinglis babelusingdeeplearningtotranslatebetweensinglecelldatasets
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