An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water.

An optimized method is presented using liquid-liquid extraction and derivatization for the extraction of iodoacetic acid (IAA) and other haloacetic acids (HAA9) and direct extraction of iodoform (IF) and other trihalomethanes (THM4) from drinking water, followed by detection by gas chromatography wi...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Xiaolin Liu, Xiao Wei, Weiwei Zheng, Songhui Jiang, Michael R Templeton, Gengsheng He, Weidong Qu
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4e0b69c42af3441ca277bb30ecf10072
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4e0b69c42af3441ca277bb30ecf10072
record_format	dspace
spelling	oai:doaj.org-article:4e0b69c42af3441ca277bb30ecf100722021-11-18T07:49:24ZAn optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water.1932-620310.1371/journal.pone.0060858https://doaj.org/article/4e0b69c42af3441ca277bb30ecf100722013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23613747/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203An optimized method is presented using liquid-liquid extraction and derivatization for the extraction of iodoacetic acid (IAA) and other haloacetic acids (HAA9) and direct extraction of iodoform (IF) and other trihalomethanes (THM4) from drinking water, followed by detection by gas chromatography with electron capture detection (GC-ECD). A Doehlert experimental design was performed to determine the optimum conditions for the five most significant factors in the derivatization step: namely, the volume and concentration of acidic methanol (optimized values = 15%, 1 mL), the volume and concentration of Na2SO4 solution (129 g/L, 8.5 mL), and the volume of saturated NaHCO3 solution (1 mL). Also, derivatization time and temperature were optimized by a two-variable Doehlert design, resulting in the following optimized parameters: an extraction time of 11 minutes for IF and THM4 and 14 minutes for IAA and HAA9; mass of anhydrous Na2SO4 of 4 g for IF and THM4 and 16 g for IAA and HAA9; derivatization time of 160 min and temperature at 40°C. Under optimal conditions, the optimized procedure achieves excellent linearity (R(2) ranges 0.9990-0.9998), low detection limits (0.0008-0.2 µg/L), low quantification limits (0.008-0.4 µg/L), and good recovery (86.6%-106.3%). Intra- and inter-day precision were less than 8.9% and 8.8%, respectively. The method was validated by applying it to the analysis of raw, flocculated, settled, and finished waters collected from a water treatment plant in China.Xiaolin LiuXiao WeiWeiwei ZhengSonghui JiangMichael R TempletonGengsheng HeWeidong QuPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 4, p e60858 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Xiaolin Liu Xiao Wei Weiwei Zheng Songhui Jiang Michael R Templeton Gengsheng He Weidong Qu An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water.
description	An optimized method is presented using liquid-liquid extraction and derivatization for the extraction of iodoacetic acid (IAA) and other haloacetic acids (HAA9) and direct extraction of iodoform (IF) and other trihalomethanes (THM4) from drinking water, followed by detection by gas chromatography with electron capture detection (GC-ECD). A Doehlert experimental design was performed to determine the optimum conditions for the five most significant factors in the derivatization step: namely, the volume and concentration of acidic methanol (optimized values = 15%, 1 mL), the volume and concentration of Na2SO4 solution (129 g/L, 8.5 mL), and the volume of saturated NaHCO3 solution (1 mL). Also, derivatization time and temperature were optimized by a two-variable Doehlert design, resulting in the following optimized parameters: an extraction time of 11 minutes for IF and THM4 and 14 minutes for IAA and HAA9; mass of anhydrous Na2SO4 of 4 g for IF and THM4 and 16 g for IAA and HAA9; derivatization time of 160 min and temperature at 40°C. Under optimal conditions, the optimized procedure achieves excellent linearity (R(2) ranges 0.9990-0.9998), low detection limits (0.0008-0.2 µg/L), low quantification limits (0.008-0.4 µg/L), and good recovery (86.6%-106.3%). Intra- and inter-day precision were less than 8.9% and 8.8%, respectively. The method was validated by applying it to the analysis of raw, flocculated, settled, and finished waters collected from a water treatment plant in China.
format	article
author	Xiaolin Liu Xiao Wei Weiwei Zheng Songhui Jiang Michael R Templeton Gengsheng He Weidong Qu
author_facet	Xiaolin Liu Xiao Wei Weiwei Zheng Songhui Jiang Michael R Templeton Gengsheng He Weidong Qu
author_sort	Xiaolin Liu
title	An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water.
title_short	An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water.
title_full	An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water.
title_fullStr	An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water.
title_full_unstemmed	An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water.
title_sort	optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/4e0b69c42af3441ca277bb30ecf10072
work_keys_str_mv	AT xiaolinliu anoptimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT xiaowei anoptimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT weiweizheng anoptimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT songhuijiang anoptimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT michaelrtempleton anoptimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT gengshenghe anoptimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT weidongqu anoptimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT xiaolinliu optimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT xiaowei optimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT weiweizheng optimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT songhuijiang optimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT michaelrtempleton optimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT gengshenghe optimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater AT weidongqu optimizedanalyticalmethodforthesimultaneousdetectionofiodoformiodoaceticacidandothertrihalomethanesandhaloaceticacidsindrinkingwater
_version_	1718422909003759616

An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water.

Ejemplares similares