Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

Reactivation of the inactive X chromosome (Xi) has modelled epigenetic reprogramming in mouse. Here, by using cell fusion between human female fibroblasts and mouse embryonic stem cells, the authors show a complex hierarchy of epigenetic changes that are required to reactivate the genes on the human...

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Autores principales:	Irene Cantone, Hakan Bagci, Dirk Dormann, Gopuraja Dharmalingam, Tatyana Nesterova, Neil Brockdorff, Claire Rougeulle, Celine Vallot, Edith Heard, Ronan Chaligne, Matthias Merkenschlager, Amanda G. Fisher
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4e0f58511c414c589feb938c38b79712
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spelling	oai:doaj.org-article:4e0f58511c414c589feb938c38b797122021-12-02T16:58:11ZOrdered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming10.1038/ncomms123542041-1723https://doaj.org/article/4e0f58511c414c589feb938c38b797122016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12354https://doaj.org/toc/2041-1723Reactivation of the inactive X chromosome (Xi) has modelled epigenetic reprogramming in mouse. Here, by using cell fusion between human female fibroblasts and mouse embryonic stem cells, the authors show a complex hierarchy of epigenetic changes that are required to reactivate the genes on the human Xi chromosome.Irene CantoneHakan BagciDirk DormannGopuraja DharmalingamTatyana NesterovaNeil BrockdorffClaire RougeulleCeline VallotEdith HeardRonan ChaligneMatthias MerkenschlagerAmanda G. FisherNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Irene Cantone Hakan Bagci Dirk Dormann Gopuraja Dharmalingam Tatyana Nesterova Neil Brockdorff Claire Rougeulle Celine Vallot Edith Heard Ronan Chaligne Matthias Merkenschlager Amanda G. Fisher Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming
description	Reactivation of the inactive X chromosome (Xi) has modelled epigenetic reprogramming in mouse. Here, by using cell fusion between human female fibroblasts and mouse embryonic stem cells, the authors show a complex hierarchy of epigenetic changes that are required to reactivate the genes on the human Xi chromosome.
format	article
author	Irene Cantone Hakan Bagci Dirk Dormann Gopuraja Dharmalingam Tatyana Nesterova Neil Brockdorff Claire Rougeulle Celine Vallot Edith Heard Ronan Chaligne Matthias Merkenschlager Amanda G. Fisher
author_facet	Irene Cantone Hakan Bagci Dirk Dormann Gopuraja Dharmalingam Tatyana Nesterova Neil Brockdorff Claire Rougeulle Celine Vallot Edith Heard Ronan Chaligne Matthias Merkenschlager Amanda G. Fisher
author_sort	Irene Cantone
title	Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming
title_short	Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming
title_full	Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming
title_fullStr	Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming
title_full_unstemmed	Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming
title_sort	ordered chromatin changes and human x chromosome reactivation by cell fusion-mediated pluripotent reprogramming
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/4e0f58511c414c589feb938c38b79712
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Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

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