INTERRELATION BETWEEN LUNGS FUNCTiONAL PARAMETERS AND CONDiTiON OF BONE TISSUE AT THE TERMINAL PULMONARY PATHOLOGY

The aim of this study was to evaluate the condition of mineral density of bone tissue at the terminal pulmonary pathology, to determine correlations between lungs functional parameters and. pre-transplantation bone mass. Materials and methods: we realized retrospective analysis of 74 case histories...

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Autores principales:	L. G. Ugay, E. A. Kochetkova, K. A. Burya, S. A. Albavichus
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	ospeoporosis terminal lung pathology lung transplantation Science Q
Acceso en línea:	https://doaj.org/article/4e131158f1e34f2cb65b6f3f294f967e
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spelling	oai:doaj.org-article:4e131158f1e34f2cb65b6f3f294f967e2021-11-23T06:14:22ZINTERRELATION BETWEEN LUNGS FUNCTiONAL PARAMETERS AND CONDiTiON OF BONE TISSUE AT THE TERMINAL PULMONARY PATHOLOGY2541-94202587-9596https://doaj.org/article/4e131158f1e34f2cb65b6f3f294f967e2012-07-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/983https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The aim of this study was to evaluate the condition of mineral density of bone tissue at the terminal pulmonary pathology, to determine correlations between lungs functional parameters and. pre-transplantation bone mass. Materials and methods: we realized retrospective analysis of 74 case histories of patients with terminal pulmonary pathology, waiting for lung transplantation. MDBT in lumbar segment of spine (L2—L4) and. femoral neck (FN) was evaluated, with help of double-energy X-ray absorptiometry (Hologic). Function of external respiration was researched, gasometry and 6-minutes walking test were realized, in all the patients. Results: osteopenic syndrome in any zone of interest was registered in 69 % of patients. Normal indices of MDBT both in L2—L4 and. in FN were registered only in 11 % of patients. On our data the indices of T-criterion (both, in L2—L4 and. in FN) had. direct relation with, body weight index (BWI) and. total fatty mass. Direct correlation between MDBT, volume of forced expiration for 1 second. (FEV) (r = 0,49, p < 0,05 in L2—L4 and. r = 0,52, p < 0,05 in FN) and. indirect correlation with, total lungs capacity (TLC) (r = —0,53, p < 0,01) with residual lungs volume (RV) (r = —0,48, p < 0,05) only in FN. We revealed, reliable negative interrelation, of MDBT only with pCO2 of arterial blood (r = —0,54, p < 0,01 in L2—L4 and r = —0,48, p < 0,05 in FN). There were no reliable correlation between DLCO, 6-minutes walking test and. MDBT both in L2—L4 and. in FN. 11% of patients had. atraumatic fractures of different localization. Conclusion: thus, osteoporosis is sufficiently frequent system, manifestation, in patients with, different terminal pulmonary pathology in pre-transplantation period. Worsening of lungs functional parameters, low BWI and. decrease of total fatty mass can be strong predictors of osteoporosis at the serious respiratory pathology.L. G. UgayE. A. KochetkovaK. A. BuryaS. A. AlbavichusScientific Сentre for Family Health and Human Reproduction Problemsarticleospeoporosisterminal lung pathologylung transplantationScienceQRUActa Biomedica Scientifica, Vol 0, Iss 4(1), Pp 122-125 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	ospeoporosis terminal lung pathology lung transplantation Science Q
spellingShingle	ospeoporosis terminal lung pathology lung transplantation Science Q L. G. Ugay E. A. Kochetkova K. A. Burya S. A. Albavichus INTERRELATION BETWEEN LUNGS FUNCTiONAL PARAMETERS AND CONDiTiON OF BONE TISSUE AT THE TERMINAL PULMONARY PATHOLOGY
description	The aim of this study was to evaluate the condition of mineral density of bone tissue at the terminal pulmonary pathology, to determine correlations between lungs functional parameters and. pre-transplantation bone mass. Materials and methods: we realized retrospective analysis of 74 case histories of patients with terminal pulmonary pathology, waiting for lung transplantation. MDBT in lumbar segment of spine (L2—L4) and. femoral neck (FN) was evaluated, with help of double-energy X-ray absorptiometry (Hologic). Function of external respiration was researched, gasometry and 6-minutes walking test were realized, in all the patients. Results: osteopenic syndrome in any zone of interest was registered in 69 % of patients. Normal indices of MDBT both in L2—L4 and. in FN were registered only in 11 % of patients. On our data the indices of T-criterion (both, in L2—L4 and. in FN) had. direct relation with, body weight index (BWI) and. total fatty mass. Direct correlation between MDBT, volume of forced expiration for 1 second. (FEV) (r = 0,49, p < 0,05 in L2—L4 and. r = 0,52, p < 0,05 in FN) and. indirect correlation with, total lungs capacity (TLC) (r = —0,53, p < 0,01) with residual lungs volume (RV) (r = —0,48, p < 0,05) only in FN. We revealed, reliable negative interrelation, of MDBT only with pCO2 of arterial blood (r = —0,54, p < 0,01 in L2—L4 and r = —0,48, p < 0,05 in FN). There were no reliable correlation between DLCO, 6-minutes walking test and. MDBT both in L2—L4 and. in FN. 11% of patients had. atraumatic fractures of different localization. Conclusion: thus, osteoporosis is sufficiently frequent system, manifestation, in patients with, different terminal pulmonary pathology in pre-transplantation period. Worsening of lungs functional parameters, low BWI and. decrease of total fatty mass can be strong predictors of osteoporosis at the serious respiratory pathology.
format	article
author	L. G. Ugay E. A. Kochetkova K. A. Burya S. A. Albavichus
author_facet	L. G. Ugay E. A. Kochetkova K. A. Burya S. A. Albavichus
author_sort	L. G. Ugay
title	INTERRELATION BETWEEN LUNGS FUNCTiONAL PARAMETERS AND CONDiTiON OF BONE TISSUE AT THE TERMINAL PULMONARY PATHOLOGY
title_short	INTERRELATION BETWEEN LUNGS FUNCTiONAL PARAMETERS AND CONDiTiON OF BONE TISSUE AT THE TERMINAL PULMONARY PATHOLOGY
title_full	INTERRELATION BETWEEN LUNGS FUNCTiONAL PARAMETERS AND CONDiTiON OF BONE TISSUE AT THE TERMINAL PULMONARY PATHOLOGY
title_fullStr	INTERRELATION BETWEEN LUNGS FUNCTiONAL PARAMETERS AND CONDiTiON OF BONE TISSUE AT THE TERMINAL PULMONARY PATHOLOGY
title_full_unstemmed	INTERRELATION BETWEEN LUNGS FUNCTiONAL PARAMETERS AND CONDiTiON OF BONE TISSUE AT THE TERMINAL PULMONARY PATHOLOGY
title_sort	interrelation between lungs functional parameters and condition of bone tissue at the terminal pulmonary pathology
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/4e131158f1e34f2cb65b6f3f294f967e
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INTERRELATION BETWEEN LUNGS FUNCTiONAL PARAMETERS AND CONDiTiON OF BONE TISSUE AT THE TERMINAL PULMONARY PATHOLOGY

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