Hierarchical progressive learning of cell identities in single-cell data

Classification methods for scRNA-seq data are limited in their ability to learn from multiple datasets simultaneously. Here the authors present scHPL, a hierarchical progressive learning method that automatically finds relationships between cell populations across multiple datasets and constructs a...

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Autores principales: Lieke Michielsen, Marcel J. T. Reinders, Ahmed Mahfouz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4e15acbcd00048f2abe98c564cc7ece7
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spelling oai:doaj.org-article:4e15acbcd00048f2abe98c564cc7ece72021-12-02T17:15:32ZHierarchical progressive learning of cell identities in single-cell data10.1038/s41467-021-23196-82041-1723https://doaj.org/article/4e15acbcd00048f2abe98c564cc7ece72021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23196-8https://doaj.org/toc/2041-1723Classification methods for scRNA-seq data are limited in their ability to learn from multiple datasets simultaneously. Here the authors present scHPL, a hierarchical progressive learning method that automatically finds relationships between cell populations across multiple datasets and constructs a classification tree.Lieke MichielsenMarcel J. T. ReindersAhmed MahfouzNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lieke Michielsen
Marcel J. T. Reinders
Ahmed Mahfouz
Hierarchical progressive learning of cell identities in single-cell data
description Classification methods for scRNA-seq data are limited in their ability to learn from multiple datasets simultaneously. Here the authors present scHPL, a hierarchical progressive learning method that automatically finds relationships between cell populations across multiple datasets and constructs a classification tree.
format article
author Lieke Michielsen
Marcel J. T. Reinders
Ahmed Mahfouz
author_facet Lieke Michielsen
Marcel J. T. Reinders
Ahmed Mahfouz
author_sort Lieke Michielsen
title Hierarchical progressive learning of cell identities in single-cell data
title_short Hierarchical progressive learning of cell identities in single-cell data
title_full Hierarchical progressive learning of cell identities in single-cell data
title_fullStr Hierarchical progressive learning of cell identities in single-cell data
title_full_unstemmed Hierarchical progressive learning of cell identities in single-cell data
title_sort hierarchical progressive learning of cell identities in single-cell data
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4e15acbcd00048f2abe98c564cc7ece7
work_keys_str_mv AT liekemichielsen hierarchicalprogressivelearningofcellidentitiesinsinglecelldata
AT marceljtreinders hierarchicalprogressivelearningofcellidentitiesinsinglecelldata
AT ahmedmahfouz hierarchicalprogressivelearningofcellidentitiesinsinglecelldata
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