Pregnant and breastfeeding women's prospective acceptability of two biomedical HIV prevention approaches in Sub Saharan Africa: A multisite qualitative analysis using the Theoretical Framework of Acceptability.

HIV infection during pregnancy and breastfeeding has implications for maternal health. Between May- November 2018, we explored prospective acceptability of two novel HIV Pre-exposure Prophylaxis (PrEP) products, oral pills and vaginal rings, through focus group discussions with 65 pregnant and breas...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Mandeep Sekhon, Ariane van der Straten, MTN-041/MAMMA Study Team
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/4e1b2e0110a6471fabe43fb35176b391
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:4e1b2e0110a6471fabe43fb35176b391
record_format dspace
spelling oai:doaj.org-article:4e1b2e0110a6471fabe43fb35176b3912021-12-02T20:13:03ZPregnant and breastfeeding women's prospective acceptability of two biomedical HIV prevention approaches in Sub Saharan Africa: A multisite qualitative analysis using the Theoretical Framework of Acceptability.1932-620310.1371/journal.pone.0259779https://doaj.org/article/4e1b2e0110a6471fabe43fb35176b3912021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0259779https://doaj.org/toc/1932-6203HIV infection during pregnancy and breastfeeding has implications for maternal health. Between May- November 2018, we explored prospective acceptability of two novel HIV Pre-exposure Prophylaxis (PrEP) products, oral pills and vaginal rings, through focus group discussions with 65 pregnant and breastfeeding women in Malawi, South Africa, Uganda, Zimbabwe. Qualitative analysis was completed, guided by the Theoretical Framework of Acceptability (TFA). First, a deductive thematic analysis was applied to relevant coded data, into the seven TFA constructs (Affective Attitude; Burden; Ethicality, Intervention Coherence; Opportunity Costs; Perceived Effectiveness; Self-efficacy). Next, an iterative analysis was completed to generate themes within each of the TFA constructs. Women's positive attitudes towards daily oral PrEP highlighted the familiarity of taking pills, understanding the purpose of taking pills, and the perception that it is an effective method to protect mothers and babies from HIV during pregnancy and breastfeeding. Women emphasized the ease of using the ring given its monthly duration that lowers burden on the user, its discreetness and invisibility once in place. The TFA analysis highlighted how acceptability of both methods could be enhanced by focusing on perceptions of the end users (i.e. the women) and not just the products themselves. This approach provided insights into how to refine the intervention materials and plans for implementation.Mandeep SekhonAriane van der StratenMTN-041/MAMMA Study TeamPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 11, p e0259779 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Mandeep Sekhon
Ariane van der Straten
MTN-041/MAMMA Study Team
Pregnant and breastfeeding women's prospective acceptability of two biomedical HIV prevention approaches in Sub Saharan Africa: A multisite qualitative analysis using the Theoretical Framework of Acceptability.
description HIV infection during pregnancy and breastfeeding has implications for maternal health. Between May- November 2018, we explored prospective acceptability of two novel HIV Pre-exposure Prophylaxis (PrEP) products, oral pills and vaginal rings, through focus group discussions with 65 pregnant and breastfeeding women in Malawi, South Africa, Uganda, Zimbabwe. Qualitative analysis was completed, guided by the Theoretical Framework of Acceptability (TFA). First, a deductive thematic analysis was applied to relevant coded data, into the seven TFA constructs (Affective Attitude; Burden; Ethicality, Intervention Coherence; Opportunity Costs; Perceived Effectiveness; Self-efficacy). Next, an iterative analysis was completed to generate themes within each of the TFA constructs. Women's positive attitudes towards daily oral PrEP highlighted the familiarity of taking pills, understanding the purpose of taking pills, and the perception that it is an effective method to protect mothers and babies from HIV during pregnancy and breastfeeding. Women emphasized the ease of using the ring given its monthly duration that lowers burden on the user, its discreetness and invisibility once in place. The TFA analysis highlighted how acceptability of both methods could be enhanced by focusing on perceptions of the end users (i.e. the women) and not just the products themselves. This approach provided insights into how to refine the intervention materials and plans for implementation.
format article
author Mandeep Sekhon
Ariane van der Straten
MTN-041/MAMMA Study Team
author_facet Mandeep Sekhon
Ariane van der Straten
MTN-041/MAMMA Study Team
author_sort Mandeep Sekhon
title Pregnant and breastfeeding women's prospective acceptability of two biomedical HIV prevention approaches in Sub Saharan Africa: A multisite qualitative analysis using the Theoretical Framework of Acceptability.
title_short Pregnant and breastfeeding women's prospective acceptability of two biomedical HIV prevention approaches in Sub Saharan Africa: A multisite qualitative analysis using the Theoretical Framework of Acceptability.
title_full Pregnant and breastfeeding women's prospective acceptability of two biomedical HIV prevention approaches in Sub Saharan Africa: A multisite qualitative analysis using the Theoretical Framework of Acceptability.
title_fullStr Pregnant and breastfeeding women's prospective acceptability of two biomedical HIV prevention approaches in Sub Saharan Africa: A multisite qualitative analysis using the Theoretical Framework of Acceptability.
title_full_unstemmed Pregnant and breastfeeding women's prospective acceptability of two biomedical HIV prevention approaches in Sub Saharan Africa: A multisite qualitative analysis using the Theoretical Framework of Acceptability.
title_sort pregnant and breastfeeding women's prospective acceptability of two biomedical hiv prevention approaches in sub saharan africa: a multisite qualitative analysis using the theoretical framework of acceptability.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/4e1b2e0110a6471fabe43fb35176b391
work_keys_str_mv AT mandeepsekhon pregnantandbreastfeedingwomensprospectiveacceptabilityoftwobiomedicalhivpreventionapproachesinsubsaharanafricaamultisitequalitativeanalysisusingthetheoreticalframeworkofacceptability
AT arianevanderstraten pregnantandbreastfeedingwomensprospectiveacceptabilityoftwobiomedicalhivpreventionapproachesinsubsaharanafricaamultisitequalitativeanalysisusingthetheoreticalframeworkofacceptability
AT mtn041mammastudyteam pregnantandbreastfeedingwomensprospectiveacceptabilityoftwobiomedicalhivpreventionapproachesinsubsaharanafricaamultisitequalitativeanalysisusingthetheoreticalframeworkofacceptability
_version_ 1718374822607585280