Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival

Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival

Through automated image analysis, Singhal et al quantify nuclear versus cytoplasmic distribution of the Kaiso transcription factor in breast cancer patient tissue. They find that Kaiso distribution correlates with breast cancer subtype and overall survival, and discover a link between cytoplasmic Ka...

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Autores principales: Sandeep K. Singhal, Jung S. Byun, Samson Park, Tingfen Yan, Ryan Yancey, Ambar Caban, Sara Gil Hernandez, Stephen M. Hewitt, Heike Boisvert, Stephanie Hennek, Mark Bobrow, Md Shakir Uddin Ahmed, Jason White, Clayton Yates, Andrew Aukerman, Rami Vanguri, Rohan Bareja, Romina Lenci, Paula Lucia Farré, Adriana De Siervi, Anna María Nápoles, Nasreen Vohra, Kevin Gardner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/4e1c6ea4c98943a8a43e8875d77bb47a
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spelling oai:doaj.org-article:4e1c6ea4c98943a8a43e8875d77bb47a2021-12-02T10:44:14ZKaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival10.1038/s42003-021-01651-y2399-3642https://doaj.org/article/4e1c6ea4c98943a8a43e8875d77bb47a2021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01651-yhttps://doaj.org/toc/2399-3642Through automated image analysis, Singhal et al quantify nuclear versus cytoplasmic distribution of the Kaiso transcription factor in breast cancer patient tissue. They find that Kaiso distribution correlates with breast cancer subtype and overall survival, and discover a link between cytoplasmic Kaiso and autophagy marker LC3.Sandeep K. SinghalJung S. ByunSamson ParkTingfen YanRyan YanceyAmbar CabanSara Gil HernandezStephen M. HewittHeike BoisvertStephanie HennekMark BobrowMd Shakir Uddin AhmedJason WhiteClayton YatesAndrew AukermanRami VanguriRohan BarejaRomina LenciPaula Lucia FarréAdriana De SierviAnna María NápolesNasreen VohraKevin GardnerNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Sandeep K. Singhal
Jung S. Byun
Samson Park
Tingfen Yan
Ryan Yancey
Ambar Caban
Sara Gil Hernandez
Stephen M. Hewitt
Heike Boisvert
Stephanie Hennek
Mark Bobrow
Md Shakir Uddin Ahmed
Jason White
Clayton Yates
Andrew Aukerman
Rami Vanguri
Rohan Bareja
Romina Lenci
Paula Lucia Farré
Adriana De Siervi
Anna María Nápoles
Nasreen Vohra
Kevin Gardner
Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival
description Through automated image analysis, Singhal et al quantify nuclear versus cytoplasmic distribution of the Kaiso transcription factor in breast cancer patient tissue. They find that Kaiso distribution correlates with breast cancer subtype and overall survival, and discover a link between cytoplasmic Kaiso and autophagy marker LC3.
format article
author Sandeep K. Singhal
Jung S. Byun
Samson Park
Tingfen Yan
Ryan Yancey
Ambar Caban
Sara Gil Hernandez
Stephen M. Hewitt
Heike Boisvert
Stephanie Hennek
Mark Bobrow
Md Shakir Uddin Ahmed
Jason White
Clayton Yates
Andrew Aukerman
Rami Vanguri
Rohan Bareja
Romina Lenci
Paula Lucia Farré
Adriana De Siervi
Anna María Nápoles
Nasreen Vohra
Kevin Gardner
author_facet Sandeep K. Singhal
Jung S. Byun
Samson Park
Tingfen Yan
Ryan Yancey
Ambar Caban
Sara Gil Hernandez
Stephen M. Hewitt
Heike Boisvert
Stephanie Hennek
Mark Bobrow
Md Shakir Uddin Ahmed
Jason White
Clayton Yates
Andrew Aukerman
Rami Vanguri
Rohan Bareja
Romina Lenci
Paula Lucia Farré
Adriana De Siervi
Anna María Nápoles
Nasreen Vohra
Kevin Gardner
author_sort Sandeep K. Singhal
title Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival
title_short Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival
title_full Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival
title_fullStr Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival
title_full_unstemmed Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival
title_sort kaiso (zbtb33) subcellular partitioning functionally links lc3a/b, the tumor microenvironment, and breast cancer survival
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4e1c6ea4c98943a8a43e8875d77bb47a
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