ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION

Abstract. Immunophenotype profile of lymphocytes (CD3+, CD4+ and CD8+) from peripheral blood in gastric ulcer associated with Helicobacter pylori, chronic gastritis and stomach cancer has been studied in Khakassian aboriginals and migrants. Apoptosis of peripheral blood lymphocytes was also evaluate...

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Autores principales: E. S. Ageeva, V. M. Iptyshev, O. V. Stygasheva, N. V. Ryasantseva
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/4e1ecf47f7d2401e8da3ffcf59f96645
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spelling oai:doaj.org-article:4e1ecf47f7d2401e8da3ffcf59f966452021-11-18T08:03:40ZETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION1563-06252313-741X10.15789/1563-0625-2012-3-249-254https://doaj.org/article/4e1ecf47f7d2401e8da3ffcf59f966452014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/364https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Immunophenotype profile of lymphocytes (CD3+, CD4+ and CD8+) from peripheral blood in gastric ulcer associated with Helicobacter pylori, chronic gastritis and stomach cancer has been studied in Khakassian aboriginals and migrants. Apoptosis of peripheral blood lymphocytes was also evaluated. Some alterations of immunological indexes were revealed in patients infected with Helicobacter pylori, as compared to healthy donors and migrants. The changes were characterized by a more intense apoptotic death of lymphocytes in the patients, when compared with numbers of apoptotic cells in control group. Probable role of apoptotic events in regulation of local and system immunity in Helicobacter pylori infection is discussed.E. S. AgeevaV. M. IptyshevO. V. StygashevaN. V. RyasantsevaSPb RAACIarticlehelicobacter pyloristomach cancergastric ulcerlymphocytescd markersapoptosisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 14, Iss 3, Pp 249-254 (2014)
institution DOAJ
collection DOAJ
language RU
topic helicobacter pylori
stomach cancer
gastric ulcer
lymphocytes
cd markers
apoptosis
Immunologic diseases. Allergy
RC581-607
spellingShingle helicobacter pylori
stomach cancer
gastric ulcer
lymphocytes
cd markers
apoptosis
Immunologic diseases. Allergy
RC581-607
E. S. Ageeva
V. M. Iptyshev
O. V. Stygasheva
N. V. Ryasantseva
ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION
description Abstract. Immunophenotype profile of lymphocytes (CD3+, CD4+ and CD8+) from peripheral blood in gastric ulcer associated with Helicobacter pylori, chronic gastritis and stomach cancer has been studied in Khakassian aboriginals and migrants. Apoptosis of peripheral blood lymphocytes was also evaluated. Some alterations of immunological indexes were revealed in patients infected with Helicobacter pylori, as compared to healthy donors and migrants. The changes were characterized by a more intense apoptotic death of lymphocytes in the patients, when compared with numbers of apoptotic cells in control group. Probable role of apoptotic events in regulation of local and system immunity in Helicobacter pylori infection is discussed.
format article
author E. S. Ageeva
V. M. Iptyshev
O. V. Stygasheva
N. V. Ryasantseva
author_facet E. S. Ageeva
V. M. Iptyshev
O. V. Stygasheva
N. V. Ryasantseva
author_sort E. S. Ageeva
title ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION
title_short ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION
title_full ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION
title_fullStr ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION
title_full_unstemmed ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION
title_sort ethnic and population-specific features of some immunological parameters in chronic helicobacter pylori infection
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/4e1ecf47f7d2401e8da3ffcf59f96645
work_keys_str_mv AT esageeva ethnicandpopulationspecificfeaturesofsomeimmunologicalparametersinchronichelicobacterpyloriinfection
AT vmiptyshev ethnicandpopulationspecificfeaturesofsomeimmunologicalparametersinchronichelicobacterpyloriinfection
AT ovstygasheva ethnicandpopulationspecificfeaturesofsomeimmunologicalparametersinchronichelicobacterpyloriinfection
AT nvryasantseva ethnicandpopulationspecificfeaturesofsomeimmunologicalparametersinchronichelicobacterpyloriinfection
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