Dual-layer spectral detector CT to study the correlation between pericoronary adipose tissue and coronary artery stenosis

Abstract Background To investigate the relationship of pericoronary adipose tissue (PCAT) with coronary artery stenosis using dual-layer spectral detector CT (SDCT). Methods 99 patients were retrospectively divided into normal group, non-significant stenosis group and significant stenosis group (n =...

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Autores principales:	Xiaolong Zhu, Xujiao Chen, Shaowei Ma, Ke Zhou, Yang Hou
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Dual-layer spectral detector Pericoronary adipose tissue Epicardial fat volume Coronary artery stenosis Plaque Surgery RD1-811 Anesthesiology RD78.3-87.3
Acceso en línea:	https://doaj.org/article/4e25e98cab6b4b29bbdef9256975a37d
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spelling	oai:doaj.org-article:4e25e98cab6b4b29bbdef9256975a37d2021-11-14T12:33:58ZDual-layer spectral detector CT to study the correlation between pericoronary adipose tissue and coronary artery stenosis10.1186/s13019-021-01709-21749-8090https://doaj.org/article/4e25e98cab6b4b29bbdef9256975a37d2021-11-01T00:00:00Zhttps://doi.org/10.1186/s13019-021-01709-2https://doaj.org/toc/1749-8090Abstract Background To investigate the relationship of pericoronary adipose tissue (PCAT) with coronary artery stenosis using dual-layer spectral detector CT (SDCT). Methods 99 patients were retrospectively divided into normal group, non-significant stenosis group and significant stenosis group (n = 33 in each group). Fat attenuation index (FAI) 40kev, spectral curve slope (λHU), effective atomic number (Eff-Z) and epicardial fat volume (EFV) were quantitatively evaluated of the narrowest part of the lesion tissue by SDCT. Results There were significant differences in PCAT parameters on SDCT (FAI40keV, λHU, Eff-Z and EFV) among the three groups (P < 0.05). FAI40keV, λHU, and Eff-Z in significant stenosis group were statistically different from those in normal group and non-significant stenosis group (P < 0.05). FAI40keV, λHU, and Eff-Z in non-significant stenosis group were statistically different from significant stenosis group (P < 0.05). EFV in normal group were significantly lower in non-significant stenosis group and significant stenosis group (P < 0.001). Univariate and multivariate logistic regression analyses identified FAI40keV (OR = 1.50, 95%CI 1.01 to 1.09) and λHU (OR = 6.81, 95%CI 1.87 to 24.86) as independent predictors of significant stenosis. FAI40keV and λHU had quite good discrimination, with an AUC of 0.84 and 0.80 respectively. Conclusion FAI40keV, λHU, and Eff-Z on SDCT in significant stenosis group were significantly different from normal and non-significant stenosis group while EFV in normal group were significantly different from non-significant stenosis group and significant stenosis group. FAI40kev and λHU were risk factors for significant stenosis.Xiaolong ZhuXujiao ChenShaowei MaKe ZhouYang HouBMCarticleDual-layer spectral detectorPericoronary adipose tissueEpicardial fat volumeCoronary artery stenosisPlaqueSurgeryRD1-811AnesthesiologyRD78.3-87.3ENJournal of Cardiothoracic Surgery, Vol 16, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Dual-layer spectral detector Pericoronary adipose tissue Epicardial fat volume Coronary artery stenosis Plaque Surgery RD1-811 Anesthesiology RD78.3-87.3
spellingShingle	Dual-layer spectral detector Pericoronary adipose tissue Epicardial fat volume Coronary artery stenosis Plaque Surgery RD1-811 Anesthesiology RD78.3-87.3 Xiaolong Zhu Xujiao Chen Shaowei Ma Ke Zhou Yang Hou Dual-layer spectral detector CT to study the correlation between pericoronary adipose tissue and coronary artery stenosis
description	Abstract Background To investigate the relationship of pericoronary adipose tissue (PCAT) with coronary artery stenosis using dual-layer spectral detector CT (SDCT). Methods 99 patients were retrospectively divided into normal group, non-significant stenosis group and significant stenosis group (n = 33 in each group). Fat attenuation index (FAI) 40kev, spectral curve slope (λHU), effective atomic number (Eff-Z) and epicardial fat volume (EFV) were quantitatively evaluated of the narrowest part of the lesion tissue by SDCT. Results There were significant differences in PCAT parameters on SDCT (FAI40keV, λHU, Eff-Z and EFV) among the three groups (P < 0.05). FAI40keV, λHU, and Eff-Z in significant stenosis group were statistically different from those in normal group and non-significant stenosis group (P < 0.05). FAI40keV, λHU, and Eff-Z in non-significant stenosis group were statistically different from significant stenosis group (P < 0.05). EFV in normal group were significantly lower in non-significant stenosis group and significant stenosis group (P < 0.001). Univariate and multivariate logistic regression analyses identified FAI40keV (OR = 1.50, 95%CI 1.01 to 1.09) and λHU (OR = 6.81, 95%CI 1.87 to 24.86) as independent predictors of significant stenosis. FAI40keV and λHU had quite good discrimination, with an AUC of 0.84 and 0.80 respectively. Conclusion FAI40keV, λHU, and Eff-Z on SDCT in significant stenosis group were significantly different from normal and non-significant stenosis group while EFV in normal group were significantly different from non-significant stenosis group and significant stenosis group. FAI40kev and λHU were risk factors for significant stenosis.
format	article
author	Xiaolong Zhu Xujiao Chen Shaowei Ma Ke Zhou Yang Hou
author_facet	Xiaolong Zhu Xujiao Chen Shaowei Ma Ke Zhou Yang Hou
author_sort	Xiaolong Zhu
title	Dual-layer spectral detector CT to study the correlation between pericoronary adipose tissue and coronary artery stenosis
title_short	Dual-layer spectral detector CT to study the correlation between pericoronary adipose tissue and coronary artery stenosis
title_full	Dual-layer spectral detector CT to study the correlation between pericoronary adipose tissue and coronary artery stenosis
title_fullStr	Dual-layer spectral detector CT to study the correlation between pericoronary adipose tissue and coronary artery stenosis
title_full_unstemmed	Dual-layer spectral detector CT to study the correlation between pericoronary adipose tissue and coronary artery stenosis
title_sort	dual-layer spectral detector ct to study the correlation between pericoronary adipose tissue and coronary artery stenosis
publisher	BMC
publishDate	2021
url	https://doaj.org/article/4e25e98cab6b4b29bbdef9256975a37d
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Dual-layer spectral detector CT to study the correlation between pericoronary adipose tissue and coronary artery stenosis

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