Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly

Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly

Androgen receptor (AR) signaling is regulated by multiple post-translational modifications. Here, the authors identify the writer and reader enzymes for AR ADP-ribosylation and show how they modulate AR signaling output in prostate cancer cells.

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Autores principales: Chun-Song Yang, Kasey Jividen, Teddy Kamata, Natalia Dworak, Luke Oostdyk, Bartlomiej Remlein, Yasin Pourfarjam, In-Kwon Kim, Kang-Ping Du, Tarek Abbas, Nicholas E. Sherman, David Wotton, Bryce M. Paschal
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4e3161d87a9e495bb19ec9d697ca2a8c
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spelling oai:doaj.org-article:4e3161d87a9e495bb19ec9d697ca2a8c2021-12-02T16:57:26ZAndrogen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly10.1038/s41467-021-23055-62041-1723https://doaj.org/article/4e3161d87a9e495bb19ec9d697ca2a8c2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23055-6https://doaj.org/toc/2041-1723Androgen receptor (AR) signaling is regulated by multiple post-translational modifications. Here, the authors identify the writer and reader enzymes for AR ADP-ribosylation and show how they modulate AR signaling output in prostate cancer cells.Chun-Song YangKasey JividenTeddy KamataNatalia DworakLuke OostdykBartlomiej RemleinYasin PourfarjamIn-Kwon KimKang-Ping DuTarek AbbasNicholas E. ShermanDavid WottonBryce M. PaschalNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chun-Song Yang
Kasey Jividen
Teddy Kamata
Natalia Dworak
Luke Oostdyk
Bartlomiej Remlein
Yasin Pourfarjam
In-Kwon Kim
Kang-Ping Du
Tarek Abbas
Nicholas E. Sherman
David Wotton
Bryce M. Paschal
Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly
description Androgen receptor (AR) signaling is regulated by multiple post-translational modifications. Here, the authors identify the writer and reader enzymes for AR ADP-ribosylation and show how they modulate AR signaling output in prostate cancer cells.
format article
author Chun-Song Yang
Kasey Jividen
Teddy Kamata
Natalia Dworak
Luke Oostdyk
Bartlomiej Remlein
Yasin Pourfarjam
In-Kwon Kim
Kang-Ping Du
Tarek Abbas
Nicholas E. Sherman
David Wotton
Bryce M. Paschal
author_facet Chun-Song Yang
Kasey Jividen
Teddy Kamata
Natalia Dworak
Luke Oostdyk
Bartlomiej Remlein
Yasin Pourfarjam
In-Kwon Kim
Kang-Ping Du
Tarek Abbas
Nicholas E. Sherman
David Wotton
Bryce M. Paschal
author_sort Chun-Song Yang
title Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly
title_short Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly
title_full Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly
title_fullStr Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly
title_full_unstemmed Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly
title_sort androgen signaling uses a writer and a reader of adp-ribosylation to regulate protein complex assembly
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4e3161d87a9e495bb19ec9d697ca2a8c
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