A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification

Sepsis is a potentially life–threatening complication of infection and diagnosis depends on rapid assessment of leukocyte count and CD64 expression. Here the authors present a microfluidic chip that can quantify these parameters from minimal amounts of whole blood with no manual processing.

Guardado en:
Detalles Bibliográficos
Autores principales: U. Hassan, T. Ghonge, B. Reddy Jr., M. Patel, M. Rappleye, I. Taneja, A. Tanna, R. Healey, N. Manusry, Z. Price, T. Jensen, J. Berger, A. Hasnain, E. Flaugher, S. Liu, B. Davis, J. Kumar, K. White, R. Bashir
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/4e330b972dd54f1d9071ee67fbca8cbe
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:4e330b972dd54f1d9071ee67fbca8cbe
record_format dspace
spelling oai:doaj.org-article:4e330b972dd54f1d9071ee67fbca8cbe2021-12-02T14:41:18ZA point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification10.1038/ncomms159492041-1723https://doaj.org/article/4e330b972dd54f1d9071ee67fbca8cbe2017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms15949https://doaj.org/toc/2041-1723Sepsis is a potentially life–threatening complication of infection and diagnosis depends on rapid assessment of leukocyte count and CD64 expression. Here the authors present a microfluidic chip that can quantify these parameters from minimal amounts of whole blood with no manual processing.U. HassanT. GhongeB. Reddy Jr.M. PatelM. RappleyeI. TanejaA. TannaR. HealeyN. ManusryZ. PriceT. JensenJ. BergerA. HasnainE. FlaugherS. LiuB. DavisJ. KumarK. WhiteR. BashirNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
U. Hassan
T. Ghonge
B. Reddy Jr.
M. Patel
M. Rappleye
I. Taneja
A. Tanna
R. Healey
N. Manusry
Z. Price
T. Jensen
J. Berger
A. Hasnain
E. Flaugher
S. Liu
B. Davis
J. Kumar
K. White
R. Bashir
A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification
description Sepsis is a potentially life–threatening complication of infection and diagnosis depends on rapid assessment of leukocyte count and CD64 expression. Here the authors present a microfluidic chip that can quantify these parameters from minimal amounts of whole blood with no manual processing.
format article
author U. Hassan
T. Ghonge
B. Reddy Jr.
M. Patel
M. Rappleye
I. Taneja
A. Tanna
R. Healey
N. Manusry
Z. Price
T. Jensen
J. Berger
A. Hasnain
E. Flaugher
S. Liu
B. Davis
J. Kumar
K. White
R. Bashir
author_facet U. Hassan
T. Ghonge
B. Reddy Jr.
M. Patel
M. Rappleye
I. Taneja
A. Tanna
R. Healey
N. Manusry
Z. Price
T. Jensen
J. Berger
A. Hasnain
E. Flaugher
S. Liu
B. Davis
J. Kumar
K. White
R. Bashir
author_sort U. Hassan
title A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification
title_short A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification
title_full A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification
title_fullStr A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification
title_full_unstemmed A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification
title_sort point-of-care microfluidic biochip for quantification of cd64 expression from whole blood for sepsis stratification
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/4e330b972dd54f1d9071ee67fbca8cbe
work_keys_str_mv AT uhassan apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT tghonge apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT breddyjr apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT mpatel apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT mrappleye apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT itaneja apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT atanna apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT rhealey apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT nmanusry apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT zprice apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT tjensen apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT jberger apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT ahasnain apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT eflaugher apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT sliu apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT bdavis apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT jkumar apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT kwhite apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT rbashir apointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT uhassan pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT tghonge pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT breddyjr pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT mpatel pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT mrappleye pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT itaneja pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT atanna pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT rhealey pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT nmanusry pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT zprice pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT tjensen pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT jberger pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT ahasnain pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT eflaugher pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT sliu pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT bdavis pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT jkumar pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT kwhite pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
AT rbashir pointofcaremicrofluidicbiochipforquantificationofcd64expressionfromwholebloodforsepsisstratification
_version_ 1718389929207136256