Potential application of proteolysis targeting chimera (PROTAC) modification technology in natural products for their targeted protein degradation

There are numerous evaluations of natural products, of which majority are food bioactives, performed up to date for their various health beneficial activities via targeting specific proteins. However, the direct identification of a targeted protein remains unexplored for natural occurring compounds....

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Auteurs principaux: Guliang Yang, Haiyan Zhong, Xinxin Xia, Zhiwen Qi, Chengzhang Wang, Shiming Li
Format: article
Langue:EN
Publié: KeAi Communications Co., Ltd. 2022
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Accès en ligne:https://doaj.org/article/4e3b3fa7827c47bb94ef853f8ea1da52
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