Intraoperative frozen section can be reduced in thyroid nodules classified as Bethesda categories V and VI

Abstract Intraoperative frozen section (FS) can be reduced during thyroid lobectomy according to the results of fine needle aspiration (FNA). We evaluated the role of intraoperative FS in thyroid nodules with different diagnostic categories of the Bethesda System for Reporting Thyroid Cytopathology...

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Autores principales:	Jing Huang, Jieli Luo, Jianshe Chen, Yang Sun, Chao Zhang, Kanlun Xu, Qin Ye, Pintong Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4e3f2aa34c264b7b9f9634ce3973534d
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spelling	oai:doaj.org-article:4e3f2aa34c264b7b9f9634ce3973534d2021-12-02T12:30:53ZIntraoperative frozen section can be reduced in thyroid nodules classified as Bethesda categories V and VI10.1038/s41598-017-05459-x2045-2322https://doaj.org/article/4e3f2aa34c264b7b9f9634ce3973534d2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-05459-xhttps://doaj.org/toc/2045-2322Abstract Intraoperative frozen section (FS) can be reduced during thyroid lobectomy according to the results of fine needle aspiration (FNA). We evaluated the role of intraoperative FS in thyroid nodules with different diagnostic categories of the Bethesda System for Reporting Thyroid Cytopathology by FNA. This retrospective study included 1,235 nodules collected via thyroidectomy with both preoperative FNA and intraoperative FS at the Second Affiliated Hospital of Zhejiang University School of Medicine, from January 2011 to January 2014. FNA cytological diagnosis was classified into six categories, based on the Bethesda system. The diagnostic findings of FNA cytology and FS histology were compared with the final histological results. 189 nodules were benign. The remainder were malignant. FS diagnosis was more accurate than FNA diagnosis for nodules classified as Bethesda Categories II, III, and IV (P < 0.05). However, the accuracy of FNA diagnosis in nodules assigned Bethesda Categories V and VI was significantly higher than that of FS (P < 0.05). FS appears be beneficial for thyroid nodules classified as Bethesda categories I through IV. FS may not be necessary in nodules diagnosed as Bethesda Categories V and VI.Jing HuangJieli LuoJianshe ChenYang SunChao ZhangKanlun XuQin YePintong HuangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-6 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jing Huang Jieli Luo Jianshe Chen Yang Sun Chao Zhang Kanlun Xu Qin Ye Pintong Huang Intraoperative frozen section can be reduced in thyroid nodules classified as Bethesda categories V and VI
description	Abstract Intraoperative frozen section (FS) can be reduced during thyroid lobectomy according to the results of fine needle aspiration (FNA). We evaluated the role of intraoperative FS in thyroid nodules with different diagnostic categories of the Bethesda System for Reporting Thyroid Cytopathology by FNA. This retrospective study included 1,235 nodules collected via thyroidectomy with both preoperative FNA and intraoperative FS at the Second Affiliated Hospital of Zhejiang University School of Medicine, from January 2011 to January 2014. FNA cytological diagnosis was classified into six categories, based on the Bethesda system. The diagnostic findings of FNA cytology and FS histology were compared with the final histological results. 189 nodules were benign. The remainder were malignant. FS diagnosis was more accurate than FNA diagnosis for nodules classified as Bethesda Categories II, III, and IV (P < 0.05). However, the accuracy of FNA diagnosis in nodules assigned Bethesda Categories V and VI was significantly higher than that of FS (P < 0.05). FS appears be beneficial for thyroid nodules classified as Bethesda categories I through IV. FS may not be necessary in nodules diagnosed as Bethesda Categories V and VI.
format	article
author	Jing Huang Jieli Luo Jianshe Chen Yang Sun Chao Zhang Kanlun Xu Qin Ye Pintong Huang
author_facet	Jing Huang Jieli Luo Jianshe Chen Yang Sun Chao Zhang Kanlun Xu Qin Ye Pintong Huang
author_sort	Jing Huang
title	Intraoperative frozen section can be reduced in thyroid nodules classified as Bethesda categories V and VI
title_short	Intraoperative frozen section can be reduced in thyroid nodules classified as Bethesda categories V and VI
title_full	Intraoperative frozen section can be reduced in thyroid nodules classified as Bethesda categories V and VI
title_fullStr	Intraoperative frozen section can be reduced in thyroid nodules classified as Bethesda categories V and VI
title_full_unstemmed	Intraoperative frozen section can be reduced in thyroid nodules classified as Bethesda categories V and VI
title_sort	intraoperative frozen section can be reduced in thyroid nodules classified as bethesda categories v and vi
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/4e3f2aa34c264b7b9f9634ce3973534d
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Intraoperative frozen section can be reduced in thyroid nodules classified as Bethesda categories V and VI

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