Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey

Abstract Dyslipidemia, a major risk factor for cardiovascular diseases, has become a global issue. Due to the variations in the prevalence of dyslipidemia, this study aimed to evaluate dyslipidemia and its associated factors in women of the Bandare-Kong Cohort Study (BKNCD). This study was conducted...

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Autores principales: Marzieh Nikparvar, Mohadeseh Khaladeh, Hadi Yousefi, Mohammadsadegh Vahidi Farashah, Behzad Moayedi, Masoumeh Kheirandish
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Publicado: Nature Portfolio 2021
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spelling oai:doaj.org-article:4e47bdab7904494b8391d385137f22032021-12-02T17:39:20ZDyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey10.1038/s41598-021-88680-z2045-2322https://doaj.org/article/4e47bdab7904494b8391d385137f22032021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88680-zhttps://doaj.org/toc/2045-2322Abstract Dyslipidemia, a major risk factor for cardiovascular diseases, has become a global issue. Due to the variations in the prevalence of dyslipidemia, this study aimed to evaluate dyslipidemia and its associated factors in women of the Bandare-Kong Cohort Study (BKNCD). This study was conducted on women from the population-based BKNCD, as part of the Prospective Epidemiological Research Studies in IrAN (PERSIAN). Sociodemographic data, medical history, and anthropometric indices were collected. Dyslipidemia was defined as any lipid abnormality including low-density lipoprotein (LDL) ≥ 160, total cholesterol (TC) ≥ 240, high-density lipoprotein (HDL) < 40, or triglyceride > 200 mg/dl. From the 2223 women in this study (mean age: 48.28 ± 9.26 years), dyslipidemia was observed in 851 (38.3%). High TC was the most common lipid abnormality (18.5%) followed by high LDL (17.7%). Dyslipidemia was most prevalent among women aged 55–70 years, the married, those with < 6 years of education, the unemployed, the overweight or obese, with low socioeconomic status, diabetes, hypertension, and high waist circumference, those using the hookah and living in urban areas. Logistic regression revealed that women with high waist-to-hip ratio (WHR) (OR = 2.22, 95% CI 1.60–3.08), those aged 45–54 years (OR = 1.34, 95% CI 1.07–1.68) and 55–70 years (OR = 1.33, 95% CI 1.03–1.72), and those living in urban areas (OR = 1.35, 95% CI 1.05–1.73) were at significantly increased risk of dyslipidemia. In addition, the results were confirmed using deep neural network models. Dyslipidemia was highly prevalent in Iranian women in the southern coastal region. Central obesity, age over 45 years, and living in urban areas appear to be relatively significant risk factors for dyslipidemia among women.Marzieh NikparvarMohadeseh KhaladehHadi YousefiMohammadsadegh Vahidi FarashahBehzad MoayediMasoumeh KheirandishNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Marzieh Nikparvar
Mohadeseh Khaladeh
Hadi Yousefi
Mohammadsadegh Vahidi Farashah
Behzad Moayedi
Masoumeh Kheirandish
Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
description Abstract Dyslipidemia, a major risk factor for cardiovascular diseases, has become a global issue. Due to the variations in the prevalence of dyslipidemia, this study aimed to evaluate dyslipidemia and its associated factors in women of the Bandare-Kong Cohort Study (BKNCD). This study was conducted on women from the population-based BKNCD, as part of the Prospective Epidemiological Research Studies in IrAN (PERSIAN). Sociodemographic data, medical history, and anthropometric indices were collected. Dyslipidemia was defined as any lipid abnormality including low-density lipoprotein (LDL) ≥ 160, total cholesterol (TC) ≥ 240, high-density lipoprotein (HDL) < 40, or triglyceride > 200 mg/dl. From the 2223 women in this study (mean age: 48.28 ± 9.26 years), dyslipidemia was observed in 851 (38.3%). High TC was the most common lipid abnormality (18.5%) followed by high LDL (17.7%). Dyslipidemia was most prevalent among women aged 55–70 years, the married, those with < 6 years of education, the unemployed, the overweight or obese, with low socioeconomic status, diabetes, hypertension, and high waist circumference, those using the hookah and living in urban areas. Logistic regression revealed that women with high waist-to-hip ratio (WHR) (OR = 2.22, 95% CI 1.60–3.08), those aged 45–54 years (OR = 1.34, 95% CI 1.07–1.68) and 55–70 years (OR = 1.33, 95% CI 1.03–1.72), and those living in urban areas (OR = 1.35, 95% CI 1.05–1.73) were at significantly increased risk of dyslipidemia. In addition, the results were confirmed using deep neural network models. Dyslipidemia was highly prevalent in Iranian women in the southern coastal region. Central obesity, age over 45 years, and living in urban areas appear to be relatively significant risk factors for dyslipidemia among women.
format article
author Marzieh Nikparvar
Mohadeseh Khaladeh
Hadi Yousefi
Mohammadsadegh Vahidi Farashah
Behzad Moayedi
Masoumeh Kheirandish
author_facet Marzieh Nikparvar
Mohadeseh Khaladeh
Hadi Yousefi
Mohammadsadegh Vahidi Farashah
Behzad Moayedi
Masoumeh Kheirandish
author_sort Marzieh Nikparvar
title Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
title_short Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
title_full Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
title_fullStr Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
title_full_unstemmed Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
title_sort dyslipidemia and its associated factors in southern iranian women, bandare-kong cohort study, a cross-sectional survey
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4e47bdab7904494b8391d385137f2203
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