The prevalence and molecular spectrum of α- and β-globin gene mutations in 14,332 families of Guangdong Province, China.

The prevalence and molecular spectrum of α- and β-globin gene mutations in 14,332 families of Guangdong Province, China.

<h4>Objective</h4>To reveal the familial prevalence and molecular variation of α- and β-globin gene mutations in Guangdong Province.<h4>Methods</h4>A total of 40,808 blood samples from 14,332 families were obtained and analyzed for both hematological and molecular parameters....

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Main Authors: Aihua Yin, Bing Li, Mingyong Luo, Longchang Xu, Li Wu, Liang Zhang, Yuanzhu Ma, Tingting Chen, Shuang Gao, Juqing Liang, Hao Guo, Danqing Qin, Jicheng Wang, Tenglong Yuan, Yixia Wang, Wei-wei Huang, Wen-Fei He, Yanxia Zhang, Chang Liu, Sujian Xia, Qingshan Chen, Qingguo Zhao, Xiaozhuang Zhang
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/4e4891b5d23b4106bbfcb799039fa66a
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