Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain

Quaking RNA binding protein (QKI) is known for its role in oligodendrocyte maturation. Here, the authors define the QKI targets in the mouse brain and show that loss of QKI disrupts the expression of cell maturation-associated genes in astrocytes in vivo.

Guardado en:

Detalles Bibliográficos
Autores principales:	Kristina Sakers, Yating Liu, Lorida Llaci, Scott M. Lee, Michael J. Vasek, Michael A. Rieger, Sean Brophy, Eric Tycksen, Renate Lewis, Susan E. Maloney, Joseph D. Dougherty
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4e48d16143194a59a45f452f5de15b87
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4e48d16143194a59a45f452f5de15b87
record_format	dspace
spelling	oai:doaj.org-article:4e48d16143194a59a45f452f5de15b872021-12-02T15:52:44ZLoss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain10.1038/s41467-021-21703-52041-1723https://doaj.org/article/4e48d16143194a59a45f452f5de15b872021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21703-5https://doaj.org/toc/2041-1723Quaking RNA binding protein (QKI) is known for its role in oligodendrocyte maturation. Here, the authors define the QKI targets in the mouse brain and show that loss of QKI disrupts the expression of cell maturation-associated genes in astrocytes in vivo.Kristina SakersYating LiuLorida LlaciScott M. LeeMichael J. VasekMichael A. RiegerSean BrophyEric TycksenRenate LewisSusan E. MaloneyJoseph D. DoughertyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kristina Sakers Yating Liu Lorida Llaci Scott M. Lee Michael J. Vasek Michael A. Rieger Sean Brophy Eric Tycksen Renate Lewis Susan E. Maloney Joseph D. Dougherty Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain
description	Quaking RNA binding protein (QKI) is known for its role in oligodendrocyte maturation. Here, the authors define the QKI targets in the mouse brain and show that loss of QKI disrupts the expression of cell maturation-associated genes in astrocytes in vivo.
format	article
author	Kristina Sakers Yating Liu Lorida Llaci Scott M. Lee Michael J. Vasek Michael A. Rieger Sean Brophy Eric Tycksen Renate Lewis Susan E. Maloney Joseph D. Dougherty
author_facet	Kristina Sakers Yating Liu Lorida Llaci Scott M. Lee Michael J. Vasek Michael A. Rieger Sean Brophy Eric Tycksen Renate Lewis Susan E. Maloney Joseph D. Dougherty
author_sort	Kristina Sakers
title	Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain
title_short	Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain
title_full	Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain
title_fullStr	Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain
title_full_unstemmed	Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain
title_sort	loss of quaking rna binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4e48d16143194a59a45f452f5de15b87
work_keys_str_mv	AT kristinasakers lossofquakingrnabindingproteindisruptstheexpressionofgenesassociatedwithastrocytematurationinmousebrain AT yatingliu lossofquakingrnabindingproteindisruptstheexpressionofgenesassociatedwithastrocytematurationinmousebrain AT loridallaci lossofquakingrnabindingproteindisruptstheexpressionofgenesassociatedwithastrocytematurationinmousebrain AT scottmlee lossofquakingrnabindingproteindisruptstheexpressionofgenesassociatedwithastrocytematurationinmousebrain AT michaeljvasek lossofquakingrnabindingproteindisruptstheexpressionofgenesassociatedwithastrocytematurationinmousebrain AT michaelarieger lossofquakingrnabindingproteindisruptstheexpressionofgenesassociatedwithastrocytematurationinmousebrain AT seanbrophy lossofquakingrnabindingproteindisruptstheexpressionofgenesassociatedwithastrocytematurationinmousebrain AT erictycksen lossofquakingrnabindingproteindisruptstheexpressionofgenesassociatedwithastrocytematurationinmousebrain AT renatelewis lossofquakingrnabindingproteindisruptstheexpressionofgenesassociatedwithastrocytematurationinmousebrain AT susanemaloney lossofquakingrnabindingproteindisruptstheexpressionofgenesassociatedwithastrocytematurationinmousebrain AT josephddougherty lossofquakingrnabindingproteindisruptstheexpressionofgenesassociatedwithastrocytematurationinmousebrain
_version_	1718385569709424640

Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain

Ejemplares similares