Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders

Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders

Placenta accreta spectrum (PAS) is a high-risk obstetrical complication associated with significant morbidity and mortality. Here the authors discover a uniquely high prevalence of circulating trophoblasts clusters in PAS and explore their diagnostic potential to augment current diagnostic modalitie...

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Autores principales: Yalda Afshar, Jiantong Dong, Pan Zhao, Lei Li, Shan Wang, Ryan Y. Zhang, Ceng Zhang, Ophelia Yin, Christina S. Han, Brett D. Einerson, Tania L. Gonzalez, Huirong Zhang, Anqi Zhou, Zhuo Yang, Shih-Jie Chou, Na Sun, Ju Cheng, Henan Zhu, Jing Wang, Tiffany X. Zhang, Yi-Te Lee, Jasmine J. Wang, Pai-Chi Teng, Peng Yang, Dongping Qi, Meiping Zhao, Myung-Shin Sim, Ruilian Zhe, Jeffrey D. Goldstein, John Williams, Xietong Wang, Qingying Zhang, Lawrence D. Platt, Chang Zou, Margareta D. Pisarska, Hsian-Rong Tseng, Yazhen Zhu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4e49a8dab8414c93b2b35b20d3a32650
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Sumario:Placenta accreta spectrum (PAS) is a high-risk obstetrical complication associated with significant morbidity and mortality. Here the authors discover a uniquely high prevalence of circulating trophoblasts clusters in PAS and explore their diagnostic potential to augment current diagnostic modalities for the early detection of PAS.

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