Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders
Placenta accreta spectrum (PAS) is a high-risk obstetrical complication associated with significant morbidity and mortality. Here the authors discover a uniquely high prevalence of circulating trophoblasts clusters in PAS and explore their diagnostic potential to augment current diagnostic modalitie...
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Nature Portfolio
2021
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oai:doaj.org-article:4e49a8dab8414c93b2b35b20d3a326502021-12-02T18:49:37ZCirculating trophoblast cell clusters for early detection of placenta accreta spectrum disorders10.1038/s41467-021-24627-22041-1723https://doaj.org/article/4e49a8dab8414c93b2b35b20d3a326502021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24627-2https://doaj.org/toc/2041-1723Placenta accreta spectrum (PAS) is a high-risk obstetrical complication associated with significant morbidity and mortality. Here the authors discover a uniquely high prevalence of circulating trophoblasts clusters in PAS and explore their diagnostic potential to augment current diagnostic modalities for the early detection of PAS.Yalda AfsharJiantong DongPan ZhaoLei LiShan WangRyan Y. ZhangCeng ZhangOphelia YinChristina S. HanBrett D. EinersonTania L. GonzalezHuirong ZhangAnqi ZhouZhuo YangShih-Jie ChouNa SunJu ChengHenan ZhuJing WangTiffany X. ZhangYi-Te LeeJasmine J. WangPai-Chi TengPeng YangDongping QiMeiping ZhaoMyung-Shin SimRuilian ZheJeffrey D. GoldsteinJohn WilliamsXietong WangQingying ZhangLawrence D. PlattChang ZouMargareta D. PisarskaHsian-Rong TsengYazhen ZhuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q Yalda Afshar Jiantong Dong Pan Zhao Lei Li Shan Wang Ryan Y. Zhang Ceng Zhang Ophelia Yin Christina S. Han Brett D. Einerson Tania L. Gonzalez Huirong Zhang Anqi Zhou Zhuo Yang Shih-Jie Chou Na Sun Ju Cheng Henan Zhu Jing Wang Tiffany X. Zhang Yi-Te Lee Jasmine J. Wang Pai-Chi Teng Peng Yang Dongping Qi Meiping Zhao Myung-Shin Sim Ruilian Zhe Jeffrey D. Goldstein John Williams Xietong Wang Qingying Zhang Lawrence D. Platt Chang Zou Margareta D. Pisarska Hsian-Rong Tseng Yazhen Zhu Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders |
description |
Placenta accreta spectrum (PAS) is a high-risk obstetrical complication associated with significant morbidity and mortality. Here the authors discover a uniquely high prevalence of circulating trophoblasts clusters in PAS and explore their diagnostic potential to augment current diagnostic modalities for the early detection of PAS. |
format |
article |
author |
Yalda Afshar Jiantong Dong Pan Zhao Lei Li Shan Wang Ryan Y. Zhang Ceng Zhang Ophelia Yin Christina S. Han Brett D. Einerson Tania L. Gonzalez Huirong Zhang Anqi Zhou Zhuo Yang Shih-Jie Chou Na Sun Ju Cheng Henan Zhu Jing Wang Tiffany X. Zhang Yi-Te Lee Jasmine J. Wang Pai-Chi Teng Peng Yang Dongping Qi Meiping Zhao Myung-Shin Sim Ruilian Zhe Jeffrey D. Goldstein John Williams Xietong Wang Qingying Zhang Lawrence D. Platt Chang Zou Margareta D. Pisarska Hsian-Rong Tseng Yazhen Zhu |
author_facet |
Yalda Afshar Jiantong Dong Pan Zhao Lei Li Shan Wang Ryan Y. Zhang Ceng Zhang Ophelia Yin Christina S. Han Brett D. Einerson Tania L. Gonzalez Huirong Zhang Anqi Zhou Zhuo Yang Shih-Jie Chou Na Sun Ju Cheng Henan Zhu Jing Wang Tiffany X. Zhang Yi-Te Lee Jasmine J. Wang Pai-Chi Teng Peng Yang Dongping Qi Meiping Zhao Myung-Shin Sim Ruilian Zhe Jeffrey D. Goldstein John Williams Xietong Wang Qingying Zhang Lawrence D. Platt Chang Zou Margareta D. Pisarska Hsian-Rong Tseng Yazhen Zhu |
author_sort |
Yalda Afshar |
title |
Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders |
title_short |
Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders |
title_full |
Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders |
title_fullStr |
Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders |
title_full_unstemmed |
Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders |
title_sort |
circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/4e49a8dab8414c93b2b35b20d3a32650 |
work_keys_str_mv |
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