Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders

Placenta accreta spectrum (PAS) is a high-risk obstetrical complication associated with significant morbidity and mortality. Here the authors discover a uniquely high prevalence of circulating trophoblasts clusters in PAS and explore their diagnostic potential to augment current diagnostic modalitie...

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Autores principales: Yalda Afshar, Jiantong Dong, Pan Zhao, Lei Li, Shan Wang, Ryan Y. Zhang, Ceng Zhang, Ophelia Yin, Christina S. Han, Brett D. Einerson, Tania L. Gonzalez, Huirong Zhang, Anqi Zhou, Zhuo Yang, Shih-Jie Chou, Na Sun, Ju Cheng, Henan Zhu, Jing Wang, Tiffany X. Zhang, Yi-Te Lee, Jasmine J. Wang, Pai-Chi Teng, Peng Yang, Dongping Qi, Meiping Zhao, Myung-Shin Sim, Ruilian Zhe, Jeffrey D. Goldstein, John Williams, Xietong Wang, Qingying Zhang, Lawrence D. Platt, Chang Zou, Margareta D. Pisarska, Hsian-Rong Tseng, Yazhen Zhu
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4e49a8dab8414c93b2b35b20d3a32650
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spelling oai:doaj.org-article:4e49a8dab8414c93b2b35b20d3a326502021-12-02T18:49:37ZCirculating trophoblast cell clusters for early detection of placenta accreta spectrum disorders10.1038/s41467-021-24627-22041-1723https://doaj.org/article/4e49a8dab8414c93b2b35b20d3a326502021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24627-2https://doaj.org/toc/2041-1723Placenta accreta spectrum (PAS) is a high-risk obstetrical complication associated with significant morbidity and mortality. Here the authors discover a uniquely high prevalence of circulating trophoblasts clusters in PAS and explore their diagnostic potential to augment current diagnostic modalities for the early detection of PAS.Yalda AfsharJiantong DongPan ZhaoLei LiShan WangRyan Y. ZhangCeng ZhangOphelia YinChristina S. HanBrett D. EinersonTania L. GonzalezHuirong ZhangAnqi ZhouZhuo YangShih-Jie ChouNa SunJu ChengHenan ZhuJing WangTiffany X. ZhangYi-Te LeeJasmine J. WangPai-Chi TengPeng YangDongping QiMeiping ZhaoMyung-Shin SimRuilian ZheJeffrey D. GoldsteinJohn WilliamsXietong WangQingying ZhangLawrence D. PlattChang ZouMargareta D. PisarskaHsian-Rong TsengYazhen ZhuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yalda Afshar
Jiantong Dong
Pan Zhao
Lei Li
Shan Wang
Ryan Y. Zhang
Ceng Zhang
Ophelia Yin
Christina S. Han
Brett D. Einerson
Tania L. Gonzalez
Huirong Zhang
Anqi Zhou
Zhuo Yang
Shih-Jie Chou
Na Sun
Ju Cheng
Henan Zhu
Jing Wang
Tiffany X. Zhang
Yi-Te Lee
Jasmine J. Wang
Pai-Chi Teng
Peng Yang
Dongping Qi
Meiping Zhao
Myung-Shin Sim
Ruilian Zhe
Jeffrey D. Goldstein
John Williams
Xietong Wang
Qingying Zhang
Lawrence D. Platt
Chang Zou
Margareta D. Pisarska
Hsian-Rong Tseng
Yazhen Zhu
Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders
description Placenta accreta spectrum (PAS) is a high-risk obstetrical complication associated with significant morbidity and mortality. Here the authors discover a uniquely high prevalence of circulating trophoblasts clusters in PAS and explore their diagnostic potential to augment current diagnostic modalities for the early detection of PAS.
format article
author Yalda Afshar
Jiantong Dong
Pan Zhao
Lei Li
Shan Wang
Ryan Y. Zhang
Ceng Zhang
Ophelia Yin
Christina S. Han
Brett D. Einerson
Tania L. Gonzalez
Huirong Zhang
Anqi Zhou
Zhuo Yang
Shih-Jie Chou
Na Sun
Ju Cheng
Henan Zhu
Jing Wang
Tiffany X. Zhang
Yi-Te Lee
Jasmine J. Wang
Pai-Chi Teng
Peng Yang
Dongping Qi
Meiping Zhao
Myung-Shin Sim
Ruilian Zhe
Jeffrey D. Goldstein
John Williams
Xietong Wang
Qingying Zhang
Lawrence D. Platt
Chang Zou
Margareta D. Pisarska
Hsian-Rong Tseng
Yazhen Zhu
author_facet Yalda Afshar
Jiantong Dong
Pan Zhao
Lei Li
Shan Wang
Ryan Y. Zhang
Ceng Zhang
Ophelia Yin
Christina S. Han
Brett D. Einerson
Tania L. Gonzalez
Huirong Zhang
Anqi Zhou
Zhuo Yang
Shih-Jie Chou
Na Sun
Ju Cheng
Henan Zhu
Jing Wang
Tiffany X. Zhang
Yi-Te Lee
Jasmine J. Wang
Pai-Chi Teng
Peng Yang
Dongping Qi
Meiping Zhao
Myung-Shin Sim
Ruilian Zhe
Jeffrey D. Goldstein
John Williams
Xietong Wang
Qingying Zhang
Lawrence D. Platt
Chang Zou
Margareta D. Pisarska
Hsian-Rong Tseng
Yazhen Zhu
author_sort Yalda Afshar
title Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders
title_short Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders
title_full Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders
title_fullStr Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders
title_full_unstemmed Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders
title_sort circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4e49a8dab8414c93b2b35b20d3a32650
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