Conservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Study

This prospective multicentric study aiming to determine the incidence of complications (malignant transformation, torsion or rupture) during conservative management of adnexal masses was performed in two Portuguese tertiary referral hospitals. It included ≥18-year-old, non-pregnant patients with asy...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Marta Espanhol Brito, André Borges, Sofia Rodrigues, Paula Ambrósio, Raquel Condeço, Abílio Lacerda, Maria José Bernardo, Patrícia Pinto, Dusan Djokovic
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	adnexal mass benign lesions conservative management IOTA ADNEX model ultrasound Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/4e49cff6aa6747d1abc9329a4ea0914e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4e49cff6aa6747d1abc9329a4ea0914e
record_format	dspace
spelling	oai:doaj.org-article:4e49cff6aa6747d1abc9329a4ea0914e2021-11-25T17:20:33ZConservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Study10.3390/diagnostics111119922075-4418https://doaj.org/article/4e49cff6aa6747d1abc9329a4ea0914e2021-10-01T00:00:00Zhttps://www.mdpi.com/2075-4418/11/11/1992https://doaj.org/toc/2075-4418This prospective multicentric study aiming to determine the incidence of complications (malignant transformation, torsion or rupture) during conservative management of adnexal masses was performed in two Portuguese tertiary referral hospitals. It included ≥18-year-old, non-pregnant patients with asymptomatic adnexal masses (associated IOTA ADNEX risk of malignancy < 10%) sonographically diagnosed between January 2016 and December 2020. Conservative patient management consisted of serial clinical and ultrasound assessment up to 60 months of follow-up, spontaneous resolution of the formation or surgical excision (median follow-up: 17.8; range 9–48 months). From the 573 masses monitored (328 premenopausal and 245 postmenopausal adnexal masses), no complications were observed in 99.5%. The annual lesion growth rates and increases in morphological complexity were similar in the premenopausal and postmenopausal patients. Spontaneous resolution, evidenced in 16.4% of the patients, was more common in the premenopausal group (<i>p</i> < 0.05). Surgical intervention was performed in 18.4% of the cases; one borderline and one invasive FIGO IA stage cancer were diagnosed. There was an isolated case of ovary torsion (0.17%). These data support conservative management as a safe option for sonographically benign, stable and asymptomatic adnexal masses before and after menopause and highlight the need for expedite treatment of symptomatic or increased-morphological-complexity lesions.Marta Espanhol BritoAndré BorgesSofia RodriguesPaula AmbrósioRaquel CondeçoAbílio LacerdaMaria José BernardoPatrícia PintoDusan DjokovicMDPI AGarticleadnexal massbenign lesionsconservative managementIOTA ADNEX modelultrasoundMedicine (General)R5-920ENDiagnostics, Vol 11, Iss 1992, p 1992 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	adnexal mass benign lesions conservative management IOTA ADNEX model ultrasound Medicine (General) R5-920
spellingShingle	adnexal mass benign lesions conservative management IOTA ADNEX model ultrasound Medicine (General) R5-920 Marta Espanhol Brito André Borges Sofia Rodrigues Paula Ambrósio Raquel Condeço Abílio Lacerda Maria José Bernardo Patrícia Pinto Dusan Djokovic Conservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Study
description	This prospective multicentric study aiming to determine the incidence of complications (malignant transformation, torsion or rupture) during conservative management of adnexal masses was performed in two Portuguese tertiary referral hospitals. It included ≥18-year-old, non-pregnant patients with asymptomatic adnexal masses (associated IOTA ADNEX risk of malignancy < 10%) sonographically diagnosed between January 2016 and December 2020. Conservative patient management consisted of serial clinical and ultrasound assessment up to 60 months of follow-up, spontaneous resolution of the formation or surgical excision (median follow-up: 17.8; range 9–48 months). From the 573 masses monitored (328 premenopausal and 245 postmenopausal adnexal masses), no complications were observed in 99.5%. The annual lesion growth rates and increases in morphological complexity were similar in the premenopausal and postmenopausal patients. Spontaneous resolution, evidenced in 16.4% of the patients, was more common in the premenopausal group (<i>p</i> < 0.05). Surgical intervention was performed in 18.4% of the cases; one borderline and one invasive FIGO IA stage cancer were diagnosed. There was an isolated case of ovary torsion (0.17%). These data support conservative management as a safe option for sonographically benign, stable and asymptomatic adnexal masses before and after menopause and highlight the need for expedite treatment of symptomatic or increased-morphological-complexity lesions.
format	article
author	Marta Espanhol Brito André Borges Sofia Rodrigues Paula Ambrósio Raquel Condeço Abílio Lacerda Maria José Bernardo Patrícia Pinto Dusan Djokovic
author_facet	Marta Espanhol Brito André Borges Sofia Rodrigues Paula Ambrósio Raquel Condeço Abílio Lacerda Maria José Bernardo Patrícia Pinto Dusan Djokovic
author_sort	Marta Espanhol Brito
title	Conservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Study
title_short	Conservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Study
title_full	Conservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Study
title_fullStr	Conservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Study
title_full_unstemmed	Conservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Study
title_sort	conservative management of asymptomatic adnexal masses classified as benign by the iota adnex model: a prospective multicenter portuguese study
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/4e49cff6aa6747d1abc9329a4ea0914e
work_keys_str_mv	AT martaespanholbrito conservativemanagementofasymptomaticadnexalmassesclassifiedasbenignbytheiotaadnexmodelaprospectivemulticenterportuguesestudy AT andreborges conservativemanagementofasymptomaticadnexalmassesclassifiedasbenignbytheiotaadnexmodelaprospectivemulticenterportuguesestudy AT sofiarodrigues conservativemanagementofasymptomaticadnexalmassesclassifiedasbenignbytheiotaadnexmodelaprospectivemulticenterportuguesestudy AT paulaambrosio conservativemanagementofasymptomaticadnexalmassesclassifiedasbenignbytheiotaadnexmodelaprospectivemulticenterportuguesestudy AT raquelcondeco conservativemanagementofasymptomaticadnexalmassesclassifiedasbenignbytheiotaadnexmodelaprospectivemulticenterportuguesestudy AT abiliolacerda conservativemanagementofasymptomaticadnexalmassesclassifiedasbenignbytheiotaadnexmodelaprospectivemulticenterportuguesestudy AT mariajosebernardo conservativemanagementofasymptomaticadnexalmassesclassifiedasbenignbytheiotaadnexmodelaprospectivemulticenterportuguesestudy AT patriciapinto conservativemanagementofasymptomaticadnexalmassesclassifiedasbenignbytheiotaadnexmodelaprospectivemulticenterportuguesestudy AT dusandjokovic conservativemanagementofasymptomaticadnexalmassesclassifiedasbenignbytheiotaadnexmodelaprospectivemulticenterportuguesestudy
_version_	1718412470023880704

Conservative Management of Asymptomatic Adnexal Masses Classified as Benign by the IOTA ADNEX Model: A Prospective Multicenter Portuguese Study

Ejemplares similares