Endothelial pannexin 1–TRPV4 channel signaling lowers pulmonary arterial pressure in mice

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Endothelial pannexin 1–TRPV4 channel signaling lowers pulmonary arterial pressure in mice

Pannexin 1 (Panx1), an ATP-efflux pathway, has been linked with inflammation in pulmonary capillaries. However, the physiological roles of endothelial Panx1 in the pulmonary vasculature are unknown. Endothelial transient receptor potential vanilloid 4 (TRPV4) channels lower pulmonary artery (PA) con...

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Autores principales:	Zdravka Daneva, Matteo Ottolini, Yen Lin Chen, Eliska Klimentova, Maniselvan Kuppusamy, Soham A Shah, Richard D Minshall, Cheikh I Seye, Victor E Laubach, Brant E Isakson, Swapnil K Sonkusare
Formato:	article
Lenguaje:	EN
Publicado:	eLife Sciences Publications Ltd 2021
Materias:	TRP channel Pannexin 1 purinergic signaling Caveolin 1 pulmonary vasculature Medicine R Science Q Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/4e52c48d21c241c0a4496dbc4db01f8d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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