Lactate induces aberration in the miR-30a–DBF4 axis to promote the development of gastric cancer and weakens the sensitivity to 5-Fu

Abstract Background Gastric cancer (GC) is one of the most common malignancies, molecular mechanism of which is still not clear. Aberrant expression of tumor-associated genes is the major cause of tumorigenesis. DBF4 is an important factor in cancers, although there is yet no report on its function...

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Auteurs principaux: Tengkai Wang, Rui Ji, Guanqun Liu, Beilei Ma, Zehua Wang, Qian Wang
Format: article
Langue:EN
Publié: BMC 2021
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Accès en ligne:https://doaj.org/article/4e62a756e9114bdb9f748b55f8914f7f
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