Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation

Purely elastic biomimetic soft materials are used to characterize the mechanical response of cells, but do not resemble real tissues. Here the authors develop a viscoelastic solid hydrogel, based on polyacrylamide, that can be tuned to closely resemble soft tissue, and show the influence of viscous...

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Autores principales:	Elisabeth E. Charrier, Katarzyna Pogoda, Rebecca G. Wells, Paul A. Janmey
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4e62cc81ae1140dd87a9b20cefce510a
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spelling	oai:doaj.org-article:4e62cc81ae1140dd87a9b20cefce510a2021-12-02T15:34:07ZControl of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation10.1038/s41467-018-02906-92041-1723https://doaj.org/article/4e62cc81ae1140dd87a9b20cefce510a2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02906-9https://doaj.org/toc/2041-1723Purely elastic biomimetic soft materials are used to characterize the mechanical response of cells, but do not resemble real tissues. Here the authors develop a viscoelastic solid hydrogel, based on polyacrylamide, that can be tuned to closely resemble soft tissue, and show the influence of viscous dissipation on cellular mechanical sensing.Elisabeth E. CharrierKatarzyna PogodaRebecca G. WellsPaul A. JanmeyNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elisabeth E. Charrier Katarzyna Pogoda Rebecca G. Wells Paul A. Janmey Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation
description	Purely elastic biomimetic soft materials are used to characterize the mechanical response of cells, but do not resemble real tissues. Here the authors develop a viscoelastic solid hydrogel, based on polyacrylamide, that can be tuned to closely resemble soft tissue, and show the influence of viscous dissipation on cellular mechanical sensing.
format	article
author	Elisabeth E. Charrier Katarzyna Pogoda Rebecca G. Wells Paul A. Janmey
author_facet	Elisabeth E. Charrier Katarzyna Pogoda Rebecca G. Wells Paul A. Janmey
author_sort	Elisabeth E. Charrier
title	Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation
title_short	Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation
title_full	Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation
title_fullStr	Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation
title_full_unstemmed	Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation
title_sort	control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/4e62cc81ae1140dd87a9b20cefce510a
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Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation

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