MORTALITY OF HIV/AIDS-INFECTED PEOPLE WITH ANTIRETROVIRAL THERAPY: A GENDER ANALYSIS

Background: Mortality in people living with HIV/AIDS is one of measures to the success of its treatment. Study related to their deaths seen from gender is still very limited. Objective: The aim of this study was to determine the incidence rate of mortality between men and women living with HIV/AID...

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Autores principales:	Putu Dian Prima Kusuma Dewi, Putu Sukma Megaputri, Lina Anggaraeni Dwijayanti, Dewa Ayu Putu Indra Pranita, Made Juniari Dewi
Formato:	article
Lenguaje:	EN
Publicado:	Belitung Raya Foundation 2018
Materias:	HIV/AIDS gender mortality antiretroviral therapy Nursing RT1-120
Acceso en línea:	https://doaj.org/article/4e67c5be6e644dcea99a1fd65db62009
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spelling	oai:doaj.org-article:4e67c5be6e644dcea99a1fd65db620092021-12-02T11:27:30ZMORTALITY OF HIV/AIDS-INFECTED PEOPLE WITH ANTIRETROVIRAL THERAPY: A GENDER ANALYSIS2477-40732477-4073https://doaj.org/article/4e67c5be6e644dcea99a1fd65db620092018-11-01T00:00:00Zhttps://belitungraya.org/BRP/index.php/bnj/article/view/571https://doaj.org/toc/2477-4073https://doaj.org/toc/2477-4073Background: Mortality in people living with HIV/AIDS is one of measures to the success of its treatment. Study related to their deaths seen from gender is still very limited. Objective: The aim of this study was to determine the incidence rate of mortality between men and women living with HIV/AIDS and receiving antiretroviral therapy. Methods: This was a retrospective study using secondary data of HIV/AIDS-infected patients in Buleleng District Hospital in the period of 2006-2015. This research used Survival analysis, Kaplan-meier, incident rate comparison and logistic regression with STATA SE 12. Results: A total of 1204 HIV/AIDS-infected patients data was included. The incidence of total mortality rates was 27.7 per 1000 person-years. Based on gender, the mortality in men (35 per 1000 person-years) was higher than women (14 per 1000 person-years) with the incidence rate ratio (IRR) of 2.39 (p 0.01). Fifty percent of cases of mortality occured at 0.15 years of observation. The median time of mortality in men was 0.14 years (1.7 months) and in women was 0.15 years (1.8 months). The poor clinical condition was seen from a body weight <50 kg, which increased the risk of death with aOR 3.85 (p 0.01 CI 2.40-6.16). Nevirapine increased the risk of mortality (aOR 2.18; p 0.01; CI 1.18-4.03). and CD4 cell counts of ≤ 200 cells / mm3 reduced the risk of death by 69% (AOR 0.31; p 0.01; CI 0.18-0.53). Conclusion: The incidence of mortality in men was greater than it in women, which is caused by poor clinical conditions. It is better to evaluate the success of antiretroviral therapy by considering the needs of patients according to their gender. Further research is needed in regard to adherence of treatment and loss to follow-up events. Putu Dian Prima Kusuma DewiPutu Sukma MegaputriLina Anggaraeni DwijayantiDewa Ayu Putu Indra PranitaMade Juniari DewiBelitung Raya FoundationarticleHIV/AIDSgendermortalityantiretroviral therapyNursingRT1-120ENBelitung Nursing Journal, Vol 4, Iss 6, Pp 559-565 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	HIV/AIDS gender mortality antiretroviral therapy Nursing RT1-120
spellingShingle	HIV/AIDS gender mortality antiretroviral therapy Nursing RT1-120 Putu Dian Prima Kusuma Dewi Putu Sukma Megaputri Lina Anggaraeni Dwijayanti Dewa Ayu Putu Indra Pranita Made Juniari Dewi MORTALITY OF HIV/AIDS-INFECTED PEOPLE WITH ANTIRETROVIRAL THERAPY: A GENDER ANALYSIS
description	Background: Mortality in people living with HIV/AIDS is one of measures to the success of its treatment. Study related to their deaths seen from gender is still very limited. Objective: The aim of this study was to determine the incidence rate of mortality between men and women living with HIV/AIDS and receiving antiretroviral therapy. Methods: This was a retrospective study using secondary data of HIV/AIDS-infected patients in Buleleng District Hospital in the period of 2006-2015. This research used Survival analysis, Kaplan-meier, incident rate comparison and logistic regression with STATA SE 12. Results: A total of 1204 HIV/AIDS-infected patients data was included. The incidence of total mortality rates was 27.7 per 1000 person-years. Based on gender, the mortality in men (35 per 1000 person-years) was higher than women (14 per 1000 person-years) with the incidence rate ratio (IRR) of 2.39 (p 0.01). Fifty percent of cases of mortality occured at 0.15 years of observation. The median time of mortality in men was 0.14 years (1.7 months) and in women was 0.15 years (1.8 months). The poor clinical condition was seen from a body weight <50 kg, which increased the risk of death with aOR 3.85 (p 0.01 CI 2.40-6.16). Nevirapine increased the risk of mortality (aOR 2.18; p 0.01; CI 1.18-4.03). and CD4 cell counts of ≤ 200 cells / mm3 reduced the risk of death by 69% (AOR 0.31; p 0.01; CI 0.18-0.53). Conclusion: The incidence of mortality in men was greater than it in women, which is caused by poor clinical conditions. It is better to evaluate the success of antiretroviral therapy by considering the needs of patients according to their gender. Further research is needed in regard to adherence of treatment and loss to follow-up events.
format	article
author	Putu Dian Prima Kusuma Dewi Putu Sukma Megaputri Lina Anggaraeni Dwijayanti Dewa Ayu Putu Indra Pranita Made Juniari Dewi
author_facet	Putu Dian Prima Kusuma Dewi Putu Sukma Megaputri Lina Anggaraeni Dwijayanti Dewa Ayu Putu Indra Pranita Made Juniari Dewi
author_sort	Putu Dian Prima Kusuma Dewi
title	MORTALITY OF HIV/AIDS-INFECTED PEOPLE WITH ANTIRETROVIRAL THERAPY: A GENDER ANALYSIS
title_short	MORTALITY OF HIV/AIDS-INFECTED PEOPLE WITH ANTIRETROVIRAL THERAPY: A GENDER ANALYSIS
title_full	MORTALITY OF HIV/AIDS-INFECTED PEOPLE WITH ANTIRETROVIRAL THERAPY: A GENDER ANALYSIS
title_fullStr	MORTALITY OF HIV/AIDS-INFECTED PEOPLE WITH ANTIRETROVIRAL THERAPY: A GENDER ANALYSIS
title_full_unstemmed	MORTALITY OF HIV/AIDS-INFECTED PEOPLE WITH ANTIRETROVIRAL THERAPY: A GENDER ANALYSIS
title_sort	mortality of hiv/aids-infected people with antiretroviral therapy: a gender analysis
publisher	Belitung Raya Foundation
publishDate	2018
url	https://doaj.org/article/4e67c5be6e644dcea99a1fd65db62009
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MORTALITY OF HIV/AIDS-INFECTED PEOPLE WITH ANTIRETROVIRAL THERAPY: A GENDER ANALYSIS

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