Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.

Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.

<h4>Background</h4>Several genome-wide association studies have recently linked a group of single nucleotide polymorphisms in the 9p21 region with cardiovascular disease. The molecular mechanisms of this link are not fully understood. We investigated five different expression microarray...

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Autores principales: Lasse Folkersen, Theodosios Kyriakou, Anuj Goel, John Peden, Anders Mälarstig, Gabrielle Paulsson-Berne, Anders Hamsten, Hugh Watkins, Anders Franco-Cereceda, Anders Gabrielsen, Per Eriksson, PROCARDIS consortia
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/4e6a32a404894831a2dc98e5e9b686a0
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