Cannabis and tobacco use prior to pregnancy and subsequent offspring birth outcomes: a 20-year intergenerational prospective cohort study

Abstract There is increasing evidence that the life-course origins of health and development begin before conception. We examined associations between timing and frequency of preconception cannabis and tobacco use and next generation preterm birth (PTB), low birth weight (LBW) and small for gestatio...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lindsey A. Hines, Elizabeth A. Spry, Margarita Moreno-Betancur, Hanafi Mohamad Husin, Denise Becker, Melissa Middleton, Jeffrey M. Craig, Lex W. Doyle, Craig A. Olsson, George Patton
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4e86ae8612e74a4f92cd9e4829ee8581
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4e86ae8612e74a4f92cd9e4829ee8581
record_format	dspace
spelling	oai:doaj.org-article:4e86ae8612e74a4f92cd9e4829ee85812021-12-02T17:08:35ZCannabis and tobacco use prior to pregnancy and subsequent offspring birth outcomes: a 20-year intergenerational prospective cohort study10.1038/s41598-021-95460-22045-2322https://doaj.org/article/4e86ae8612e74a4f92cd9e4829ee85812021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95460-2https://doaj.org/toc/2045-2322Abstract There is increasing evidence that the life-course origins of health and development begin before conception. We examined associations between timing and frequency of preconception cannabis and tobacco use and next generation preterm birth (PTB), low birth weight (LBW) and small for gestational age. 665 participants in a general population cohort were repeatedly assessed on tobacco and cannabis use between ages 14–29 years, before pregnancy. Associations were estimated using logistic regression. Preconception parent (either maternal or paternal) daily cannabis use age 15–17 was associated with sixfold increases in the odds of offspring PTB (aOR 6.65, 95% CI 1.92, 23.09), and offspring LBW (aOR 5.84, 95% CI 1.70–20.08), after adjusting for baseline sociodemographic factors, parent sex, offspring sex, family socioeconomic status, parent mental health at baseline, and concurrent tobacco use. There was little evidence of associations with preconception parental cannabis use at other ages or preconception parental tobacco use. Findings support the hypothesis that the early life origins of growth begin before conception and provide a compelling rationale for prevention of frequent use during adolescence. This is pertinent given liberalisation of cannabis policy.Lindsey A. HinesElizabeth A. SpryMargarita Moreno-BetancurHanafi Mohamad HusinDenise BeckerMelissa MiddletonJeffrey M. CraigLex W. DoyleCraig A. OlssonGeorge PattonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lindsey A. Hines Elizabeth A. Spry Margarita Moreno-Betancur Hanafi Mohamad Husin Denise Becker Melissa Middleton Jeffrey M. Craig Lex W. Doyle Craig A. Olsson George Patton Cannabis and tobacco use prior to pregnancy and subsequent offspring birth outcomes: a 20-year intergenerational prospective cohort study
description	Abstract There is increasing evidence that the life-course origins of health and development begin before conception. We examined associations between timing and frequency of preconception cannabis and tobacco use and next generation preterm birth (PTB), low birth weight (LBW) and small for gestational age. 665 participants in a general population cohort were repeatedly assessed on tobacco and cannabis use between ages 14–29 years, before pregnancy. Associations were estimated using logistic regression. Preconception parent (either maternal or paternal) daily cannabis use age 15–17 was associated with sixfold increases in the odds of offspring PTB (aOR 6.65, 95% CI 1.92, 23.09), and offspring LBW (aOR 5.84, 95% CI 1.70–20.08), after adjusting for baseline sociodemographic factors, parent sex, offspring sex, family socioeconomic status, parent mental health at baseline, and concurrent tobacco use. There was little evidence of associations with preconception parental cannabis use at other ages or preconception parental tobacco use. Findings support the hypothesis that the early life origins of growth begin before conception and provide a compelling rationale for prevention of frequent use during adolescence. This is pertinent given liberalisation of cannabis policy.
format	article
author	Lindsey A. Hines Elizabeth A. Spry Margarita Moreno-Betancur Hanafi Mohamad Husin Denise Becker Melissa Middleton Jeffrey M. Craig Lex W. Doyle Craig A. Olsson George Patton
author_facet	Lindsey A. Hines Elizabeth A. Spry Margarita Moreno-Betancur Hanafi Mohamad Husin Denise Becker Melissa Middleton Jeffrey M. Craig Lex W. Doyle Craig A. Olsson George Patton
author_sort	Lindsey A. Hines
title	Cannabis and tobacco use prior to pregnancy and subsequent offspring birth outcomes: a 20-year intergenerational prospective cohort study
title_short	Cannabis and tobacco use prior to pregnancy and subsequent offspring birth outcomes: a 20-year intergenerational prospective cohort study
title_full	Cannabis and tobacco use prior to pregnancy and subsequent offspring birth outcomes: a 20-year intergenerational prospective cohort study
title_fullStr	Cannabis and tobacco use prior to pregnancy and subsequent offspring birth outcomes: a 20-year intergenerational prospective cohort study
title_full_unstemmed	Cannabis and tobacco use prior to pregnancy and subsequent offspring birth outcomes: a 20-year intergenerational prospective cohort study
title_sort	cannabis and tobacco use prior to pregnancy and subsequent offspring birth outcomes: a 20-year intergenerational prospective cohort study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4e86ae8612e74a4f92cd9e4829ee8581
work_keys_str_mv	AT lindseyahines cannabisandtobaccousepriortopregnancyandsubsequentoffspringbirthoutcomesa20yearintergenerationalprospectivecohortstudy AT elizabethaspry cannabisandtobaccousepriortopregnancyandsubsequentoffspringbirthoutcomesa20yearintergenerationalprospectivecohortstudy AT margaritamorenobetancur cannabisandtobaccousepriortopregnancyandsubsequentoffspringbirthoutcomesa20yearintergenerationalprospectivecohortstudy AT hanafimohamadhusin cannabisandtobaccousepriortopregnancyandsubsequentoffspringbirthoutcomesa20yearintergenerationalprospectivecohortstudy AT denisebecker cannabisandtobaccousepriortopregnancyandsubsequentoffspringbirthoutcomesa20yearintergenerationalprospectivecohortstudy AT melissamiddleton cannabisandtobaccousepriortopregnancyandsubsequentoffspringbirthoutcomesa20yearintergenerationalprospectivecohortstudy AT jeffreymcraig cannabisandtobaccousepriortopregnancyandsubsequentoffspringbirthoutcomesa20yearintergenerationalprospectivecohortstudy AT lexwdoyle cannabisandtobaccousepriortopregnancyandsubsequentoffspringbirthoutcomesa20yearintergenerationalprospectivecohortstudy AT craigaolsson cannabisandtobaccousepriortopregnancyandsubsequentoffspringbirthoutcomesa20yearintergenerationalprospectivecohortstudy AT georgepatton cannabisandtobaccousepriortopregnancyandsubsequentoffspringbirthoutcomesa20yearintergenerationalprospectivecohortstudy
_version_	1718381549401931776

Cannabis and tobacco use prior to pregnancy and subsequent offspring birth outcomes: a 20-year intergenerational prospective cohort study

Ejemplares similares