K-Ras-ERK1/2 accelerates lung cancer cell development via mediating H3K18ac through the MDM2-GCN5-SIRT7 axis
Context: H3K18ac is linked to gene expression and DNA damage. Nevertheless, whether H3K18ac participates in regulating Ras-ERK1/2-affected lung cancer cell phenotypes remains unclear. Objective: We explored the effects of H3K18ac on Ras-ERK1/2-affected lung cancer cell phenotypes. Material and metho...
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Autores principales: | Ziming Cheng, Xiufeng Li, Shizhen Hou, Yubing Wu, Yi Sun, Bing Liu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Taylor & Francis Group
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/4e8ad3df0db042418be82e2594026467 |
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