Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET

Higher organisms regulate cellular iron concentrations through Iron Regulatory Proteins (IRPs), which regulate specific messenger RNAs. Here Huynh et al. show that IRP1 requires a Glycogen Branching Enzyme for proper function, and that IRP1 has additional regulatory roles in cell nuclei.

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Autores principales:	Nhan Huynh, Qiuxiang Ou, Pendleton Cox, Roland Lill, Kirst King-Jones
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4e8b650540394120baea3a101dd8b36d
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spelling	oai:doaj.org-article:4e8b650540394120baea3a101dd8b36d2021-12-02T17:01:51ZGlycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET10.1038/s41467-019-13237-82041-1723https://doaj.org/article/4e8b650540394120baea3a101dd8b36d2019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13237-8https://doaj.org/toc/2041-1723Higher organisms regulate cellular iron concentrations through Iron Regulatory Proteins (IRPs), which regulate specific messenger RNAs. Here Huynh et al. show that IRP1 requires a Glycogen Branching Enzyme for proper function, and that IRP1 has additional regulatory roles in cell nuclei.Nhan HuynhQiuxiang OuPendleton CoxRoland LillKirst King-JonesNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nhan Huynh Qiuxiang Ou Pendleton Cox Roland Lill Kirst King-Jones Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET
description	Higher organisms regulate cellular iron concentrations through Iron Regulatory Proteins (IRPs), which regulate specific messenger RNAs. Here Huynh et al. show that IRP1 requires a Glycogen Branching Enzyme for proper function, and that IRP1 has additional regulatory roles in cell nuclei.
format	article
author	Nhan Huynh Qiuxiang Ou Pendleton Cox Roland Lill Kirst King-Jones
author_facet	Nhan Huynh Qiuxiang Ou Pendleton Cox Roland Lill Kirst King-Jones
author_sort	Nhan Huynh
title	Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET
title_short	Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET
title_full	Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET
title_fullStr	Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET
title_full_unstemmed	Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET
title_sort	glycogen branching enzyme controls cellular iron homeostasis via iron regulatory protein 1 and mitoneet
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/4e8b650540394120baea3a101dd8b36d
work_keys_str_mv	AT nhanhuynh glycogenbranchingenzymecontrolscellularironhomeostasisviaironregulatoryprotein1andmitoneet AT qiuxiangou glycogenbranchingenzymecontrolscellularironhomeostasisviaironregulatoryprotein1andmitoneet AT pendletoncox glycogenbranchingenzymecontrolscellularironhomeostasisviaironregulatoryprotein1andmitoneet AT rolandlill glycogenbranchingenzymecontrolscellularironhomeostasisviaironregulatoryprotein1andmitoneet AT kirstkingjones glycogenbranchingenzymecontrolscellularironhomeostasisviaironregulatoryprotein1andmitoneet
_version_	1718382027198169088

Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET

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