Goals for rheumatoid arthritis: treating to target or treating to prevent?

Min Yang, Mingyang GuoRheumatology Center, PLA General Hospital of Chengdu Military Area Command, Chengdu, Sichuan Province, PR ChinaAlthough treat-to-target goals for rheumatoid arthritis (RA) have been well-established through several guidelines in recent years, concerns regarding treat-to-prevent...

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Autores principales:	Yang M, Guo MY
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/4e8ea355607f49929223c523b15f829c
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spelling	oai:doaj.org-article:4e8ea355607f49929223c523b15f829c2021-12-02T08:47:05ZGoals for rheumatoid arthritis: treating to target or treating to prevent?1179-156Xhttps://doaj.org/article/4e8ea355607f49929223c523b15f829c2012-07-01T00:00:00Zhttp://www.dovepress.com/goals-for-rheumatoid-arthritis-treating-to-target-or-treating-to-preve-a10349https://doaj.org/toc/1179-156XMin Yang, Mingyang GuoRheumatology Center, PLA General Hospital of Chengdu Military Area Command, Chengdu, Sichuan Province, PR ChinaAlthough treat-to-target goals for rheumatoid arthritis (RA) have been well-established through several guidelines in recent years, concerns regarding treat-to-prevent goals for RA remain unclear. RA patients are typically subjected to over- or under-treatment because it is difficult for clinicians to determine the prognosis of RA patients. This typically results in failure to select and identify patient subsets that should receive monotherapy or combination therapy to treat early RA. Understanding treat-to-prevent goals, as well as unfavorable prognoses, risk factors, and prediction methods for RA, is therefore critical for making treatment decisions. Rapid radiographic progression plays a central role in contributing to other composite RA indices, so this may be the best method for defining treat-to-prevent goals for RA. Accordingly, risk factors of rapid radiographic progression have been defined and two prediction models were retrospectively derived based on clinical trial data. Additional studies are required to develop risk models that can be used for accurate predictions.Keywords: rapid radiographic progression, prognosis, risk factors, prediction modelsYang MGuo MYDove Medical PressarticleDiseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol 2012, Iss default, Pp 81-86 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the musculoskeletal system RC925-935
spellingShingle	Diseases of the musculoskeletal system RC925-935 Yang M Guo MY Goals for rheumatoid arthritis: treating to target or treating to prevent?
description	Min Yang, Mingyang GuoRheumatology Center, PLA General Hospital of Chengdu Military Area Command, Chengdu, Sichuan Province, PR ChinaAlthough treat-to-target goals for rheumatoid arthritis (RA) have been well-established through several guidelines in recent years, concerns regarding treat-to-prevent goals for RA remain unclear. RA patients are typically subjected to over- or under-treatment because it is difficult for clinicians to determine the prognosis of RA patients. This typically results in failure to select and identify patient subsets that should receive monotherapy or combination therapy to treat early RA. Understanding treat-to-prevent goals, as well as unfavorable prognoses, risk factors, and prediction methods for RA, is therefore critical for making treatment decisions. Rapid radiographic progression plays a central role in contributing to other composite RA indices, so this may be the best method for defining treat-to-prevent goals for RA. Accordingly, risk factors of rapid radiographic progression have been defined and two prediction models were retrospectively derived based on clinical trial data. Additional studies are required to develop risk models that can be used for accurate predictions.Keywords: rapid radiographic progression, prognosis, risk factors, prediction models
format	article
author	Yang M Guo MY
author_facet	Yang M Guo MY
author_sort	Yang M
title	Goals for rheumatoid arthritis: treating to target or treating to prevent?
title_short	Goals for rheumatoid arthritis: treating to target or treating to prevent?
title_full	Goals for rheumatoid arthritis: treating to target or treating to prevent?
title_fullStr	Goals for rheumatoid arthritis: treating to target or treating to prevent?
title_full_unstemmed	Goals for rheumatoid arthritis: treating to target or treating to prevent?
title_sort	goals for rheumatoid arthritis: treating to target or treating to prevent?
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/4e8ea355607f49929223c523b15f829c
work_keys_str_mv	AT yangm goalsforrheumatoidarthritistreatingtotargetortreatingtoprevent AT guomy goalsforrheumatoidarthritistreatingtotargetortreatingtoprevent
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Goals for rheumatoid arthritis: treating to target or treating to prevent?

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