Mathematical modeling of N-803 treatment in SIV-infected non-human primates.

Mathematical modeling of N-803 treatment in SIV-infected non-human primates.

Immunomodulatory drugs could contribute to a functional cure for Human Immunodeficiency Virus (HIV). Interleukin-15 (IL-15) promotes expansion and activation of CD8+ T cell and natural killer (NK) cell populations. In one study, an IL-15 superagonist, N-803, suppressed Simian Immunodeficiency Virus...

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Autores principales: Jonathan W Cody, Amy L Ellis-Connell, Shelby L O'Connor, Elsje Pienaar
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/4ea60d8b24654b1abf4701de6935195b
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