Ni(II)-catalyzed asymmetric alkenylations of ketimines

Chiral allylic amines are often encountered in bioactive compounds and can be conveniently transformed into other chiral amines. Here, the authors report nickel-catalyzed enantioselective addition and addition/ring-expansion of alkenylboronic acids to ketimines providing a range of valuable chiral a...

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Autores principales: Mao Quan, Xiaoxiao Wang, Liang Wu, Ilya D. Gridnev, Guoqiang Yang, Wanbin Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/4ea6fbe9e6e64457912e14a2869e2fe1
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spelling oai:doaj.org-article:4ea6fbe9e6e64457912e14a2869e2fe12021-12-02T16:56:55ZNi(II)-catalyzed asymmetric alkenylations of ketimines10.1038/s41467-018-04645-32041-1723https://doaj.org/article/4ea6fbe9e6e64457912e14a2869e2fe12018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04645-3https://doaj.org/toc/2041-1723Chiral allylic amines are often encountered in bioactive compounds and can be conveniently transformed into other chiral amines. Here, the authors report nickel-catalyzed enantioselective addition and addition/ring-expansion of alkenylboronic acids to ketimines providing a range of valuable chiral azaheterocycles.Mao QuanXiaoxiao WangLiang WuIlya D. GridnevGuoqiang YangWanbin ZhangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mao Quan
Xiaoxiao Wang
Liang Wu
Ilya D. Gridnev
Guoqiang Yang
Wanbin Zhang
Ni(II)-catalyzed asymmetric alkenylations of ketimines
description Chiral allylic amines are often encountered in bioactive compounds and can be conveniently transformed into other chiral amines. Here, the authors report nickel-catalyzed enantioselective addition and addition/ring-expansion of alkenylboronic acids to ketimines providing a range of valuable chiral azaheterocycles.
format article
author Mao Quan
Xiaoxiao Wang
Liang Wu
Ilya D. Gridnev
Guoqiang Yang
Wanbin Zhang
author_facet Mao Quan
Xiaoxiao Wang
Liang Wu
Ilya D. Gridnev
Guoqiang Yang
Wanbin Zhang
author_sort Mao Quan
title Ni(II)-catalyzed asymmetric alkenylations of ketimines
title_short Ni(II)-catalyzed asymmetric alkenylations of ketimines
title_full Ni(II)-catalyzed asymmetric alkenylations of ketimines
title_fullStr Ni(II)-catalyzed asymmetric alkenylations of ketimines
title_full_unstemmed Ni(II)-catalyzed asymmetric alkenylations of ketimines
title_sort ni(ii)-catalyzed asymmetric alkenylations of ketimines
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/4ea6fbe9e6e64457912e14a2869e2fe1
work_keys_str_mv AT maoquan niiicatalyzedasymmetricalkenylationsofketimines
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AT liangwu niiicatalyzedasymmetricalkenylationsofketimines
AT ilyadgridnev niiicatalyzedasymmetricalkenylationsofketimines
AT guoqiangyang niiicatalyzedasymmetricalkenylationsofketimines
AT wanbinzhang niiicatalyzedasymmetricalkenylationsofketimines
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