Personalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum

Tapia-Alveal, Olsen and Worgall develop a novel strategy for patient-specific multiple myeloma diagnostics platform using DNA aptamers. The high affinity DNA aptamers enabled detection of minimal residual disease (MRD) when conventional MRD methods assessed complete remission and are adaptable to mu...

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Autores principales:	Claudia Tapia-Alveal, Timothy R. Olsen, Tilla S. Worgall
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/4eae892611494e1689d790423c725031
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spelling	oai:doaj.org-article:4eae892611494e1689d790423c7250312021-12-02T13:56:15ZPersonalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum10.1038/s42003-020-01515-x2399-3642https://doaj.org/article/4eae892611494e1689d790423c7250312020-12-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01515-xhttps://doaj.org/toc/2399-3642Tapia-Alveal, Olsen and Worgall develop a novel strategy for patient-specific multiple myeloma diagnostics platform using DNA aptamers. The high affinity DNA aptamers enabled detection of minimal residual disease (MRD) when conventional MRD methods assessed complete remission and are adaptable to multiple diagnostic formats including point-of-care devices.Claudia Tapia-AlvealTimothy R. OlsenTilla S. WorgallNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Claudia Tapia-Alveal Timothy R. Olsen Tilla S. Worgall Personalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum
description	Tapia-Alveal, Olsen and Worgall develop a novel strategy for patient-specific multiple myeloma diagnostics platform using DNA aptamers. The high affinity DNA aptamers enabled detection of minimal residual disease (MRD) when conventional MRD methods assessed complete remission and are adaptable to multiple diagnostic formats including point-of-care devices.
format	article
author	Claudia Tapia-Alveal Timothy R. Olsen Tilla S. Worgall
author_facet	Claudia Tapia-Alveal Timothy R. Olsen Tilla S. Worgall
author_sort	Claudia Tapia-Alveal
title	Personalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum
title_short	Personalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum
title_full	Personalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum
title_fullStr	Personalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum
title_full_unstemmed	Personalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum
title_sort	personalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4eae892611494e1689d790423c725031
work_keys_str_mv	AT claudiatapiaalveal personalizedimmunoglobulinaptamersfordetectionofmultiplemyelomaminimalresidualdiseaseinserum AT timothyrolsen personalizedimmunoglobulinaptamersfordetectionofmultiplemyelomaminimalresidualdiseaseinserum AT tillasworgall personalizedimmunoglobulinaptamersfordetectionofmultiplemyelomaminimalresidualdiseaseinserum
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Personalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum

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