The Y chromosome of autochthonous Basque populations and the Bronze Age replacement

Abstract Here we report on the Y haplogroup and Y-STR diversity of the three autochthonous Basque populations of Alava (n = 54), Guipuzcoa (n = 30) and Vizcaya (n = 61). The same samples genotyped for Y-chromosome SNPs were typed for 17 Y-STR loci (DYS19, DYS385a/b, DYS398I/II, DYS390, DYS391, DYS39...

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Autores principales:	Javier Rodriguez Luis, Leire Palencia-Madrid, Vivian C. Mendoza, Ralph Garcia-Bertrand, Marian M. de Pancorbo, Rene J. Herrera
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4eb0c60c8e904cc6be96341bd4a01e2a
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spelling	oai:doaj.org-article:4eb0c60c8e904cc6be96341bd4a01e2a2021-12-02T15:52:59ZThe Y chromosome of autochthonous Basque populations and the Bronze Age replacement10.1038/s41598-021-84915-12045-2322https://doaj.org/article/4eb0c60c8e904cc6be96341bd4a01e2a2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84915-1https://doaj.org/toc/2045-2322Abstract Here we report on the Y haplogroup and Y-STR diversity of the three autochthonous Basque populations of Alava (n = 54), Guipuzcoa (n = 30) and Vizcaya (n = 61). The same samples genotyped for Y-chromosome SNPs were typed for 17 Y-STR loci (DYS19, DYS385a/b, DYS398I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, Y-GATA H4) using the AmpFlSTR Yfiler system. Six major haplogroups (R, I, E, J, G, and DE) were detected, being R-S116 (P312) haplogroup the most abundant at 75.0% in Alava, 86.7% in Guipuzcoa and 87.3% in Vizcaya. Age estimates for the R-S116 mutation in the Basque Country are 3975 ± 303, 3680 ± 345 and 4553 ± 285 years for Alava, Guipuzcoa and Vizcaya, respectively. Pairwise Rst genetic distances demonstrated close Y-chromosome affinities among the three autochthonous Basque populations and between them and the male population of Ireland and Gascony. In a MDS plot, the population of Ireland segregates within the Basque cluster and closest to the population of Guipuzcoa, which plots closer to Ireland than to any of the other Basque populations. Overall, the results support the notion that during the Bronze Age a dispersal of individuals carrying the R-S116 mutation reached the Basque Country replacing the Paleolithic/Neolithic Y chromosome of the region.Javier Rodriguez LuisLeire Palencia-MadridVivian C. MendozaRalph Garcia-BertrandMarian M. de PancorboRene J. HerreraNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Javier Rodriguez Luis Leire Palencia-Madrid Vivian C. Mendoza Ralph Garcia-Bertrand Marian M. de Pancorbo Rene J. Herrera The Y chromosome of autochthonous Basque populations and the Bronze Age replacement
description	Abstract Here we report on the Y haplogroup and Y-STR diversity of the three autochthonous Basque populations of Alava (n = 54), Guipuzcoa (n = 30) and Vizcaya (n = 61). The same samples genotyped for Y-chromosome SNPs were typed for 17 Y-STR loci (DYS19, DYS385a/b, DYS398I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, Y-GATA H4) using the AmpFlSTR Yfiler system. Six major haplogroups (R, I, E, J, G, and DE) were detected, being R-S116 (P312) haplogroup the most abundant at 75.0% in Alava, 86.7% in Guipuzcoa and 87.3% in Vizcaya. Age estimates for the R-S116 mutation in the Basque Country are 3975 ± 303, 3680 ± 345 and 4553 ± 285 years for Alava, Guipuzcoa and Vizcaya, respectively. Pairwise Rst genetic distances demonstrated close Y-chromosome affinities among the three autochthonous Basque populations and between them and the male population of Ireland and Gascony. In a MDS plot, the population of Ireland segregates within the Basque cluster and closest to the population of Guipuzcoa, which plots closer to Ireland than to any of the other Basque populations. Overall, the results support the notion that during the Bronze Age a dispersal of individuals carrying the R-S116 mutation reached the Basque Country replacing the Paleolithic/Neolithic Y chromosome of the region.
format	article
author	Javier Rodriguez Luis Leire Palencia-Madrid Vivian C. Mendoza Ralph Garcia-Bertrand Marian M. de Pancorbo Rene J. Herrera
author_facet	Javier Rodriguez Luis Leire Palencia-Madrid Vivian C. Mendoza Ralph Garcia-Bertrand Marian M. de Pancorbo Rene J. Herrera
author_sort	Javier Rodriguez Luis
title	The Y chromosome of autochthonous Basque populations and the Bronze Age replacement
title_short	The Y chromosome of autochthonous Basque populations and the Bronze Age replacement
title_full	The Y chromosome of autochthonous Basque populations and the Bronze Age replacement
title_fullStr	The Y chromosome of autochthonous Basque populations and the Bronze Age replacement
title_full_unstemmed	The Y chromosome of autochthonous Basque populations and the Bronze Age replacement
title_sort	y chromosome of autochthonous basque populations and the bronze age replacement
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4eb0c60c8e904cc6be96341bd4a01e2a
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The Y chromosome of autochthonous Basque populations and the Bronze Age replacement

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