Expression of the Ebola Virus VP24 Protein Compromises the Integrity of the Nuclear Envelope and Induces a Laminopathy-Like Cellular Phenotype
ABSTRACT Ebola virus (EBOV) VP24 protein is a nucleocapsid-associated protein that inhibits interferon (IFN) gene expression and counteracts the IFN-mediated antiviral response, preventing nuclear import of signal transducer and activator of transcription 1 (STAT1). Proteomic studies to identify add...
Saved in:
Main Authors: | Santiago Vidal, Maite Sánchez-Aparicio, Rocío Seoane, Ahmed El Motiam, Emily V. Nelson, Yanis H. Bouzaher, Maite Baz-Martínez, Isabel García-Dorival, Susana Gonzalo, Enrique Vázquez, Anxo Vidal, César Muñoz-Fontela, Adolfo García-Sastre, Carmen Rivas |
---|---|
Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/4ebc5e9dbfd7490c8149d9b1444d153f |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Ébola: caracterización, historia y manifestaciones cutáneas; lo que debemos saber
by: Kolbach,Marianne, et al.
Published: (2015) -
Preclinical Advances of Therapies for Laminopathies
by: Louise Benarroch, et al.
Published: (2021) -
Ebola virus disease: Essential clinical knowledge
by: Mahmoud Tawfik Khalafallah, et al.
Published: (2017) -
Functional Importance of Hydrophobic Patches on the Ebola Virus VP35 IFN-Inhibitory Domain
by: Nodoka Kasajima, et al.
Published: (2021) -
Tolerance and Persistence of Ebola Virus in Primary Cells from <i>Mops condylurus</i>, a Potential Ebola Virus Reservoir
by: Marcel Bokelmann, et al.
Published: (2021)