Discovery and validation of DNA hypomethylation biomarkers for liver cancer using HRM-specific probes.

Discovery and validation of DNA hypomethylation biomarkers for liver cancer using HRM-specific probes.

Poor prognosis of hepatocellular carcinoma (HCC) associated with late diagnosis necessitates the development of early diagnostic biomarkers. We have previously delineated the landscape of DNA methylation in HCC patients unraveling the importance of promoter hypomethylation in activation of cancer- a...

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Main Authors: Barbara Stefanska, Aurelie Bouzelmat, Jian Huang, Matthew Suderman, Michael Hallett, Ze-Guang Han, Mamun Al-Mahtab, Sheikh Mohammad Fazle Akbar, Wasif Ali Khan, Rubhana Raqib, Moshe Szyf
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/4ebfda4443a54d268ec3e4fa2c648e54
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