Inhibition of miR-96-5p in the mouse brain increases glutathione levels by altering NOVA1 expression

Chisato Kinoshita et al. use a microbubble and ultrasound delivery system to inhibit miR-96-5p in the mouse brain. They demonstrate that miR96-5p regulates glutathione levels through the NOVA1 RNA binding protein, suggesting that this microRNA could be a target for altering glutathione levels in neu...

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Main Authors: Chisato Kinoshita, Kazue Kikuchi-Utsumi, Koji Aoyama, Ryo Suzuki, Yayoi Okamoto, Nobuko Matsumura, Daiki Omata, Kazuo Maruyama, Toshio Nakaki
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/4ec843332a5e4a27be302abc87f8c949
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