Biotransformation of polyunsaturated fatty acids to bioactive hepoxilins and trioxilins by microbial enzymes

Hepoxilins (HXs) and trioxilins (TrXs) are lipid metabolites with roles in inflammation and insulin secretion. Here, the authors discover a prokaryotic source of HXs and TrXs, identify the biosynthetic enzymes and heterologously express HXs and TrXs in E. coli.

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Autores principales:	Jung-Ung An, Yong-Seok Song, Kyoung-Rok Kim, Yoon-Joo Ko, Do-Young Yoon, Deok-Kun Oh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4eccf8226b724d98950131c8b9cb8b3e
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spelling	oai:doaj.org-article:4eccf8226b724d98950131c8b9cb8b3e2021-12-02T16:56:41ZBiotransformation of polyunsaturated fatty acids to bioactive hepoxilins and trioxilins by microbial enzymes10.1038/s41467-017-02543-82041-1723https://doaj.org/article/4eccf8226b724d98950131c8b9cb8b3e2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02543-8https://doaj.org/toc/2041-1723Hepoxilins (HXs) and trioxilins (TrXs) are lipid metabolites with roles in inflammation and insulin secretion. Here, the authors discover a prokaryotic source of HXs and TrXs, identify the biosynthetic enzymes and heterologously express HXs and TrXs in E. coli.Jung-Ung AnYong-Seok SongKyoung-Rok KimYoon-Joo KoDo-Young YoonDeok-Kun OhNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jung-Ung An Yong-Seok Song Kyoung-Rok Kim Yoon-Joo Ko Do-Young Yoon Deok-Kun Oh Biotransformation of polyunsaturated fatty acids to bioactive hepoxilins and trioxilins by microbial enzymes
description	Hepoxilins (HXs) and trioxilins (TrXs) are lipid metabolites with roles in inflammation and insulin secretion. Here, the authors discover a prokaryotic source of HXs and TrXs, identify the biosynthetic enzymes and heterologously express HXs and TrXs in E. coli.
format	article
author	Jung-Ung An Yong-Seok Song Kyoung-Rok Kim Yoon-Joo Ko Do-Young Yoon Deok-Kun Oh
author_facet	Jung-Ung An Yong-Seok Song Kyoung-Rok Kim Yoon-Joo Ko Do-Young Yoon Deok-Kun Oh
author_sort	Jung-Ung An
title	Biotransformation of polyunsaturated fatty acids to bioactive hepoxilins and trioxilins by microbial enzymes
title_short	Biotransformation of polyunsaturated fatty acids to bioactive hepoxilins and trioxilins by microbial enzymes
title_full	Biotransformation of polyunsaturated fatty acids to bioactive hepoxilins and trioxilins by microbial enzymes
title_fullStr	Biotransformation of polyunsaturated fatty acids to bioactive hepoxilins and trioxilins by microbial enzymes
title_full_unstemmed	Biotransformation of polyunsaturated fatty acids to bioactive hepoxilins and trioxilins by microbial enzymes
title_sort	biotransformation of polyunsaturated fatty acids to bioactive hepoxilins and trioxilins by microbial enzymes
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/4eccf8226b724d98950131c8b9cb8b3e
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Biotransformation of polyunsaturated fatty acids to bioactive hepoxilins and trioxilins by microbial enzymes

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