X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB

Guan and Hariharan report two crystal structures of melibiose transporter MelB in complex with substrate analogs, nitrophenyl-galactoside, and dodecyl-melibioside. Both structures revealed similar specific site for sugar recognition and resolved the cation-binding pocket, advancing the understanding...

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Autores principales: Lan Guan, Parameswaran Hariharan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4ed773bcbbe34592b3e96145426c9b47
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