Chronic colitis upregulates microRNAs suppressing brain-derived neurotrophic factor in the adult heart.

Ulcerative colitis and Crohn's disease are classified as chronic inflammatory bowel diseases (IBD) with known extraintestinal manifestations. The interplay between heart and gut in IBD has previously been noted, but the mechanisms remain elusive. Our objective was to identify microRNAs mediatin...

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Autores principales: Yanbo Tang, Kevin T Kline, Xiaoying S Zhong, Ying Xiao, Haifeng Lian, Jun Peng, Xiaowei Liu, Don W Powell, Guodu Tang, Qingjie Li
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/4ed7c329efcb417b875c3d91722f200a
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