Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE
How transposable elements (TE) contribute to cell fate changes is unclear. Here, the authors generate a pipeline to quantify TE expression from single cell data. They show the dynamic expression of TEs from gastrulation to somatic cell reprogramming and human disease
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Nature Portfolio
2021
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oai:doaj.org-article:4ed9c74b80c94fd98b07d31c04585b6c2021-12-02T13:34:48ZIdentifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE10.1038/s41467-021-21808-x2041-1723https://doaj.org/article/4ed9c74b80c94fd98b07d31c04585b6c2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21808-xhttps://doaj.org/toc/2041-1723How transposable elements (TE) contribute to cell fate changes is unclear. Here, the authors generate a pipeline to quantify TE expression from single cell data. They show the dynamic expression of TEs from gastrulation to somatic cell reprogramming and human diseaseJiangping HeIsaac A. BabarindeLi SunShuyang XuRuhai ChenJunjie ShiYuanjie WeiYuhao LiGang MaQiang ZhuangAndrew P. HutchinsJiekai ChenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q Jiangping He Isaac A. Babarinde Li Sun Shuyang Xu Ruhai Chen Junjie Shi Yuanjie Wei Yuhao Li Gang Ma Qiang Zhuang Andrew P. Hutchins Jiekai Chen Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE |
description |
How transposable elements (TE) contribute to cell fate changes is unclear. Here, the authors generate a pipeline to quantify TE expression from single cell data. They show the dynamic expression of TEs from gastrulation to somatic cell reprogramming and human disease |
format |
article |
author |
Jiangping He Isaac A. Babarinde Li Sun Shuyang Xu Ruhai Chen Junjie Shi Yuanjie Wei Yuhao Li Gang Ma Qiang Zhuang Andrew P. Hutchins Jiekai Chen |
author_facet |
Jiangping He Isaac A. Babarinde Li Sun Shuyang Xu Ruhai Chen Junjie Shi Yuanjie Wei Yuhao Li Gang Ma Qiang Zhuang Andrew P. Hutchins Jiekai Chen |
author_sort |
Jiangping He |
title |
Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE |
title_short |
Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE |
title_full |
Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE |
title_fullStr |
Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE |
title_full_unstemmed |
Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE |
title_sort |
identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scte |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/4ed9c74b80c94fd98b07d31c04585b6c |
work_keys_str_mv |
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