Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE

How transposable elements (TE) contribute to cell fate changes is unclear. Here, the authors generate a pipeline to quantify TE expression from single cell data. They show the dynamic expression of TEs from gastrulation to somatic cell reprogramming and human disease

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Autores principales: Jiangping He, Isaac A. Babarinde, Li Sun, Shuyang Xu, Ruhai Chen, Junjie Shi, Yuanjie Wei, Yuhao Li, Gang Ma, Qiang Zhuang, Andrew P. Hutchins, Jiekai Chen
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4ed9c74b80c94fd98b07d31c04585b6c
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spelling oai:doaj.org-article:4ed9c74b80c94fd98b07d31c04585b6c2021-12-02T13:34:48ZIdentifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE10.1038/s41467-021-21808-x2041-1723https://doaj.org/article/4ed9c74b80c94fd98b07d31c04585b6c2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21808-xhttps://doaj.org/toc/2041-1723How transposable elements (TE) contribute to cell fate changes is unclear. Here, the authors generate a pipeline to quantify TE expression from single cell data. They show the dynamic expression of TEs from gastrulation to somatic cell reprogramming and human diseaseJiangping HeIsaac A. BabarindeLi SunShuyang XuRuhai ChenJunjie ShiYuanjie WeiYuhao LiGang MaQiang ZhuangAndrew P. HutchinsJiekai ChenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jiangping He
Isaac A. Babarinde
Li Sun
Shuyang Xu
Ruhai Chen
Junjie Shi
Yuanjie Wei
Yuhao Li
Gang Ma
Qiang Zhuang
Andrew P. Hutchins
Jiekai Chen
Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE
description How transposable elements (TE) contribute to cell fate changes is unclear. Here, the authors generate a pipeline to quantify TE expression from single cell data. They show the dynamic expression of TEs from gastrulation to somatic cell reprogramming and human disease
format article
author Jiangping He
Isaac A. Babarinde
Li Sun
Shuyang Xu
Ruhai Chen
Junjie Shi
Yuanjie Wei
Yuhao Li
Gang Ma
Qiang Zhuang
Andrew P. Hutchins
Jiekai Chen
author_facet Jiangping He
Isaac A. Babarinde
Li Sun
Shuyang Xu
Ruhai Chen
Junjie Shi
Yuanjie Wei
Yuhao Li
Gang Ma
Qiang Zhuang
Andrew P. Hutchins
Jiekai Chen
author_sort Jiangping He
title Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE
title_short Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE
title_full Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE
title_fullStr Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE
title_full_unstemmed Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE
title_sort identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scte
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4ed9c74b80c94fd98b07d31c04585b6c
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