Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates

Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates

The diversity of primary sensory neurons and how fate choice is determined is unclear. Here, the authors use single cell RNA sequencing analysis of early murine somatosensory neurons to show that sensory neuron diversity is achieved by a transition through a bi-potential intermediate state.

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Detalles Bibliográficos
Autores principales: Louis Faure, Yiqiao Wang, Maria Eleni Kastriti, Paula Fontanet, Kylie K. Y. Cheung, Charles Petitpré, Haohao Wu, Lynn Linyu Sun, Karen Runge, Laura Croci, Mark A. Landy, Helen C. Lai, Gian Giacomo Consalez, Antoine de Chevigny, François Lallemend, Igor Adameyko, Saida Hadjab
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/4ee3b977689a4036812beca33045a00e
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Descripción
Sumario:The diversity of primary sensory neurons and how fate choice is determined is unclear. Here, the authors use single cell RNA sequencing analysis of early murine somatosensory neurons to show that sensory neuron diversity is achieved by a transition through a bi-potential intermediate state.

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