Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates

The diversity of primary sensory neurons and how fate choice is determined is unclear. Here, the authors use single cell RNA sequencing analysis of early murine somatosensory neurons to show that sensory neuron diversity is achieved by a transition through a bi-potential intermediate state.

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Autores principales: Louis Faure, Yiqiao Wang, Maria Eleni Kastriti, Paula Fontanet, Kylie K. Y. Cheung, Charles Petitpré, Haohao Wu, Lynn Linyu Sun, Karen Runge, Laura Croci, Mark A. Landy, Helen C. Lai, Gian Giacomo Consalez, Antoine de Chevigny, François Lallemend, Igor Adameyko, Saida Hadjab
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/4ee3b977689a4036812beca33045a00e
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spelling oai:doaj.org-article:4ee3b977689a4036812beca33045a00e2021-12-02T18:01:13ZSingle cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates10.1038/s41467-020-17929-42041-1723https://doaj.org/article/4ee3b977689a4036812beca33045a00e2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17929-4https://doaj.org/toc/2041-1723The diversity of primary sensory neurons and how fate choice is determined is unclear. Here, the authors use single cell RNA sequencing analysis of early murine somatosensory neurons to show that sensory neuron diversity is achieved by a transition through a bi-potential intermediate state.Louis FaureYiqiao WangMaria Eleni KastritiPaula FontanetKylie K. Y. CheungCharles PetitpréHaohao WuLynn Linyu SunKaren RungeLaura CrociMark A. LandyHelen C. LaiGian Giacomo ConsalezAntoine de ChevignyFrançois LallemendIgor AdameykoSaida HadjabNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Louis Faure
Yiqiao Wang
Maria Eleni Kastriti
Paula Fontanet
Kylie K. Y. Cheung
Charles Petitpré
Haohao Wu
Lynn Linyu Sun
Karen Runge
Laura Croci
Mark A. Landy
Helen C. Lai
Gian Giacomo Consalez
Antoine de Chevigny
François Lallemend
Igor Adameyko
Saida Hadjab
Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates
description The diversity of primary sensory neurons and how fate choice is determined is unclear. Here, the authors use single cell RNA sequencing analysis of early murine somatosensory neurons to show that sensory neuron diversity is achieved by a transition through a bi-potential intermediate state.
format article
author Louis Faure
Yiqiao Wang
Maria Eleni Kastriti
Paula Fontanet
Kylie K. Y. Cheung
Charles Petitpré
Haohao Wu
Lynn Linyu Sun
Karen Runge
Laura Croci
Mark A. Landy
Helen C. Lai
Gian Giacomo Consalez
Antoine de Chevigny
François Lallemend
Igor Adameyko
Saida Hadjab
author_facet Louis Faure
Yiqiao Wang
Maria Eleni Kastriti
Paula Fontanet
Kylie K. Y. Cheung
Charles Petitpré
Haohao Wu
Lynn Linyu Sun
Karen Runge
Laura Croci
Mark A. Landy
Helen C. Lai
Gian Giacomo Consalez
Antoine de Chevigny
François Lallemend
Igor Adameyko
Saida Hadjab
author_sort Louis Faure
title Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates
title_short Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates
title_full Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates
title_fullStr Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates
title_full_unstemmed Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates
title_sort single cell rna sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/4ee3b977689a4036812beca33045a00e
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