Generic Pharmaceuticals as a Source of Diuretic Contamination in Athletes Subject to Sport Drug Testing

This paper describes nine instances of positive anti-doping tests that could be accounted for by the use of permitted generic prescription drugs contaminated with diuretics, which are prohibited in sport at all times under the WADA Prohibited List. The contamination levels found in the medications a...

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Autores principales:	Amy Eichner, Laura A. Lewis, Bridget Leonard, Ryan M. Van Wagoner, Daniel Eichner, Matthew N. Fedoruk
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	prescription medication anti-doping rule violation minimum reporting level adverse analytical finding Sports GV557-1198.995
Acceso en línea:	https://doaj.org/article/4eef0f70092f49fe8daacc537daa353a
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spelling	oai:doaj.org-article:4eef0f70092f49fe8daacc537daa353a2021-11-17T07:05:24ZGeneric Pharmaceuticals as a Source of Diuretic Contamination in Athletes Subject to Sport Drug Testing2624-936710.3389/fspor.2021.692244https://doaj.org/article/4eef0f70092f49fe8daacc537daa353a2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fspor.2021.692244/fullhttps://doaj.org/toc/2624-9367This paper describes nine instances of positive anti-doping tests that could be accounted for by the use of permitted generic prescription drugs contaminated with diuretics, which are prohibited in sport at all times under the WADA Prohibited List. The contamination levels found in the medications are reported and were below FDA limits for manufacturers that are based primarily on safety considerations. These cases demonstrate that great care must be taken to identify the source of low-level anti-doping positives for diuretics reported by WADA-accredited laboratories, and possibly other prohibited substances as well, in order to avoid sanctioning innocent athletes. An evaluation of the cases in this paper supports an approach which establishes a laboratory minimum reporting level (MRL) for diuretics found most commonly in medications. A global consensus after extensive review of similar anti-doping cases has resulted in implementation of a recently announced solution regarding potential diuretic contamination cases.Amy EichnerLaura A. LewisBridget LeonardRyan M. Van WagonerDaniel EichnerMatthew N. FedorukFrontiers Media S.A.articleprescription medicationanti-dopingrule violationminimum reporting leveladverse analytical findingSportsGV557-1198.995ENFrontiers in Sports and Active Living, Vol 3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	prescription medication anti-doping rule violation minimum reporting level adverse analytical finding Sports GV557-1198.995
spellingShingle	prescription medication anti-doping rule violation minimum reporting level adverse analytical finding Sports GV557-1198.995 Amy Eichner Laura A. Lewis Bridget Leonard Ryan M. Van Wagoner Daniel Eichner Matthew N. Fedoruk Generic Pharmaceuticals as a Source of Diuretic Contamination in Athletes Subject to Sport Drug Testing
description	This paper describes nine instances of positive anti-doping tests that could be accounted for by the use of permitted generic prescription drugs contaminated with diuretics, which are prohibited in sport at all times under the WADA Prohibited List. The contamination levels found in the medications are reported and were below FDA limits for manufacturers that are based primarily on safety considerations. These cases demonstrate that great care must be taken to identify the source of low-level anti-doping positives for diuretics reported by WADA-accredited laboratories, and possibly other prohibited substances as well, in order to avoid sanctioning innocent athletes. An evaluation of the cases in this paper supports an approach which establishes a laboratory minimum reporting level (MRL) for diuretics found most commonly in medications. A global consensus after extensive review of similar anti-doping cases has resulted in implementation of a recently announced solution regarding potential diuretic contamination cases.
format	article
author	Amy Eichner Laura A. Lewis Bridget Leonard Ryan M. Van Wagoner Daniel Eichner Matthew N. Fedoruk
author_facet	Amy Eichner Laura A. Lewis Bridget Leonard Ryan M. Van Wagoner Daniel Eichner Matthew N. Fedoruk
author_sort	Amy Eichner
title	Generic Pharmaceuticals as a Source of Diuretic Contamination in Athletes Subject to Sport Drug Testing
title_short	Generic Pharmaceuticals as a Source of Diuretic Contamination in Athletes Subject to Sport Drug Testing
title_full	Generic Pharmaceuticals as a Source of Diuretic Contamination in Athletes Subject to Sport Drug Testing
title_fullStr	Generic Pharmaceuticals as a Source of Diuretic Contamination in Athletes Subject to Sport Drug Testing
title_full_unstemmed	Generic Pharmaceuticals as a Source of Diuretic Contamination in Athletes Subject to Sport Drug Testing
title_sort	generic pharmaceuticals as a source of diuretic contamination in athletes subject to sport drug testing
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/4eef0f70092f49fe8daacc537daa353a
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Generic Pharmaceuticals as a Source of Diuretic Contamination in Athletes Subject to Sport Drug Testing

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