Alternate subunit assembly diversifies the function of a bacterial toxin

Salmonella Typhi produces the typhoid toxin. Here, Fowler et al. show that S. Typhi produces two forms of typhoid toxin that are differentially regulated and display different trafficking properties and different effects when administered to laboratory animals.

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Autores principales: Casey C. Fowler, Gabrielle Stack, Xuyao Jiao, Maria Lara-Tejero, Jorge E. Galán
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/4ef4c66184da419daeb906136af36518
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spelling oai:doaj.org-article:4ef4c66184da419daeb906136af365182021-12-02T14:35:37ZAlternate subunit assembly diversifies the function of a bacterial toxin10.1038/s41467-019-11592-02041-1723https://doaj.org/article/4ef4c66184da419daeb906136af365182019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11592-0https://doaj.org/toc/2041-1723Salmonella Typhi produces the typhoid toxin. Here, Fowler et al. show that S. Typhi produces two forms of typhoid toxin that are differentially regulated and display different trafficking properties and different effects when administered to laboratory animals.Casey C. FowlerGabrielle StackXuyao JiaoMaria Lara-TejeroJorge E. GalánNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Casey C. Fowler
Gabrielle Stack
Xuyao Jiao
Maria Lara-Tejero
Jorge E. Galán
Alternate subunit assembly diversifies the function of a bacterial toxin
description Salmonella Typhi produces the typhoid toxin. Here, Fowler et al. show that S. Typhi produces two forms of typhoid toxin that are differentially regulated and display different trafficking properties and different effects when administered to laboratory animals.
format article
author Casey C. Fowler
Gabrielle Stack
Xuyao Jiao
Maria Lara-Tejero
Jorge E. Galán
author_facet Casey C. Fowler
Gabrielle Stack
Xuyao Jiao
Maria Lara-Tejero
Jorge E. Galán
author_sort Casey C. Fowler
title Alternate subunit assembly diversifies the function of a bacterial toxin
title_short Alternate subunit assembly diversifies the function of a bacterial toxin
title_full Alternate subunit assembly diversifies the function of a bacterial toxin
title_fullStr Alternate subunit assembly diversifies the function of a bacterial toxin
title_full_unstemmed Alternate subunit assembly diversifies the function of a bacterial toxin
title_sort alternate subunit assembly diversifies the function of a bacterial toxin
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/4ef4c66184da419daeb906136af36518
work_keys_str_mv AT caseycfowler alternatesubunitassemblydiversifiesthefunctionofabacterialtoxin
AT gabriellestack alternatesubunitassemblydiversifiesthefunctionofabacterialtoxin
AT xuyaojiao alternatesubunitassemblydiversifiesthefunctionofabacterialtoxin
AT marialaratejero alternatesubunitassemblydiversifiesthefunctionofabacterialtoxin
AT jorgeegalan alternatesubunitassemblydiversifiesthefunctionofabacterialtoxin
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