Alternate subunit assembly diversifies the function of a bacterial toxin
Salmonella Typhi produces the typhoid toxin. Here, Fowler et al. show that S. Typhi produces two forms of typhoid toxin that are differentially regulated and display different trafficking properties and different effects when administered to laboratory animals.
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Nature Portfolio
2019
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oai:doaj.org-article:4ef4c66184da419daeb906136af365182021-12-02T14:35:37ZAlternate subunit assembly diversifies the function of a bacterial toxin10.1038/s41467-019-11592-02041-1723https://doaj.org/article/4ef4c66184da419daeb906136af365182019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11592-0https://doaj.org/toc/2041-1723Salmonella Typhi produces the typhoid toxin. Here, Fowler et al. show that S. Typhi produces two forms of typhoid toxin that are differentially regulated and display different trafficking properties and different effects when administered to laboratory animals.Casey C. FowlerGabrielle StackXuyao JiaoMaria Lara-TejeroJorge E. GalánNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q Casey C. Fowler Gabrielle Stack Xuyao Jiao Maria Lara-Tejero Jorge E. Galán Alternate subunit assembly diversifies the function of a bacterial toxin |
description |
Salmonella Typhi produces the typhoid toxin. Here, Fowler et al. show that S. Typhi produces two forms of typhoid toxin that are differentially regulated and display different trafficking properties and different effects when administered to laboratory animals. |
format |
article |
author |
Casey C. Fowler Gabrielle Stack Xuyao Jiao Maria Lara-Tejero Jorge E. Galán |
author_facet |
Casey C. Fowler Gabrielle Stack Xuyao Jiao Maria Lara-Tejero Jorge E. Galán |
author_sort |
Casey C. Fowler |
title |
Alternate subunit assembly diversifies the function of a bacterial toxin |
title_short |
Alternate subunit assembly diversifies the function of a bacterial toxin |
title_full |
Alternate subunit assembly diversifies the function of a bacterial toxin |
title_fullStr |
Alternate subunit assembly diversifies the function of a bacterial toxin |
title_full_unstemmed |
Alternate subunit assembly diversifies the function of a bacterial toxin |
title_sort |
alternate subunit assembly diversifies the function of a bacterial toxin |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/4ef4c66184da419daeb906136af36518 |
work_keys_str_mv |
AT caseycfowler alternatesubunitassemblydiversifiesthefunctionofabacterialtoxin AT gabriellestack alternatesubunitassemblydiversifiesthefunctionofabacterialtoxin AT xuyaojiao alternatesubunitassemblydiversifiesthefunctionofabacterialtoxin AT marialaratejero alternatesubunitassemblydiversifiesthefunctionofabacterialtoxin AT jorgeegalan alternatesubunitassemblydiversifiesthefunctionofabacterialtoxin |
_version_ |
1718391069484253184 |