Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer

Cobalamin-containing reductive dehalogenases from organohalide-respiring bacteria play a key role in the degradation of halogenated organic compounds. Here the authors proposed a catalytic mechanism for dehalogenation that relies on a long-range electron transfer from the cobalt in the centre of the...

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Autores principales:	Cindy Kunze, Martin Bommer, Wilfred R. Hagen, Marie Uksa, Holger Dobbek, Torsten Schubert, Gabriele Diekert
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4ef98d22b5c14599a6650b05ec8abfcc
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spelling	oai:doaj.org-article:4ef98d22b5c14599a6650b05ec8abfcc2021-12-02T17:06:11ZCobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer10.1038/ncomms158582041-1723https://doaj.org/article/4ef98d22b5c14599a6650b05ec8abfcc2017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms15858https://doaj.org/toc/2041-1723Cobalamin-containing reductive dehalogenases from organohalide-respiring bacteria play a key role in the degradation of halogenated organic compounds. Here the authors proposed a catalytic mechanism for dehalogenation that relies on a long-range electron transfer from the cobalt in the centre of the enzyme’s cofactor to the substrate.Cindy KunzeMartin BommerWilfred R. HagenMarie UksaHolger DobbekTorsten SchubertGabriele DiekertNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cindy Kunze Martin Bommer Wilfred R. Hagen Marie Uksa Holger Dobbek Torsten Schubert Gabriele Diekert Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer
description	Cobalamin-containing reductive dehalogenases from organohalide-respiring bacteria play a key role in the degradation of halogenated organic compounds. Here the authors proposed a catalytic mechanism for dehalogenation that relies on a long-range electron transfer from the cobalt in the centre of the enzyme’s cofactor to the substrate.
format	article
author	Cindy Kunze Martin Bommer Wilfred R. Hagen Marie Uksa Holger Dobbek Torsten Schubert Gabriele Diekert
author_facet	Cindy Kunze Martin Bommer Wilfred R. Hagen Marie Uksa Holger Dobbek Torsten Schubert Gabriele Diekert
author_sort	Cindy Kunze
title	Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer
title_short	Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer
title_full	Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer
title_fullStr	Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer
title_full_unstemmed	Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer
title_sort	cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/4ef98d22b5c14599a6650b05ec8abfcc
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Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer

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