Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair

The mechanism through which Drosha and Dicer affect DNA repair is not clear. Here the authors use a high-throughput approach to uncover the role of Drosha in promoting DNA:RNA hybrids at DNA damaged sites.

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Autores principales:	Wei-Ting Lu, Ben R. Hawley, George L. Skalka, Robert A. Baldock, Ewan M. Smith, Aldo S. Bader, Michal Malewicz, Felicity Z. Watts, Ania Wilczynska, Martin Bushell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4f06c76c0d594080bebcce6e6a2b7046
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spelling	oai:doaj.org-article:4f06c76c0d594080bebcce6e6a2b70462021-12-02T13:24:16ZDrosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair10.1038/s41467-018-02893-x2041-1723https://doaj.org/article/4f06c76c0d594080bebcce6e6a2b70462018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02893-xhttps://doaj.org/toc/2041-1723The mechanism through which Drosha and Dicer affect DNA repair is not clear. Here the authors use a high-throughput approach to uncover the role of Drosha in promoting DNA:RNA hybrids at DNA damaged sites.Wei-Ting LuBen R. HawleyGeorge L. SkalkaRobert A. BaldockEwan M. SmithAldo S. BaderMichal MalewiczFelicity Z. WattsAnia WilczynskaMartin BushellNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wei-Ting Lu Ben R. Hawley George L. Skalka Robert A. Baldock Ewan M. Smith Aldo S. Bader Michal Malewicz Felicity Z. Watts Ania Wilczynska Martin Bushell Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair
description	The mechanism through which Drosha and Dicer affect DNA repair is not clear. Here the authors use a high-throughput approach to uncover the role of Drosha in promoting DNA:RNA hybrids at DNA damaged sites.
format	article
author	Wei-Ting Lu Ben R. Hawley George L. Skalka Robert A. Baldock Ewan M. Smith Aldo S. Bader Michal Malewicz Felicity Z. Watts Ania Wilczynska Martin Bushell
author_facet	Wei-Ting Lu Ben R. Hawley George L. Skalka Robert A. Baldock Ewan M. Smith Aldo S. Bader Michal Malewicz Felicity Z. Watts Ania Wilczynska Martin Bushell
author_sort	Wei-Ting Lu
title	Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair
title_short	Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair
title_full	Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair
title_fullStr	Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair
title_full_unstemmed	Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair
title_sort	drosha drives the formation of dna:rna hybrids around dna break sites to facilitate dna repair
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/4f06c76c0d594080bebcce6e6a2b7046
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Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair

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