Inhibition of poly(ADP-ribose) polymerase interferes with Trypanosoma cruzi infection and proliferation of the parasite.

Poly(ADP-ribosylation) is a post-translational covalent modification of proteins catalyzed by a family of enzymes termed poly(ADP-ribose) polymerases (PARPs). In the human genome, 17 different genes have been identified that encode members of the PARP superfamily. Poly (ADP-ribose) metabolism plays...

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Auteurs principaux: Salomé C Vilchez Larrea, Teemu Haikarainen, Mohit Narwal, Mariana Schlesinger, Harikanth Venkannagari, Mirtha M Flawiá, Silvia H Fernández Villamil, Lari Lehtiö
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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R
Q
Accès en ligne:https://doaj.org/article/4f1ce57c0d7f44758a1fe1246f865b22
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