Type 2 diabetes therapeutic strategies: why don't we see the «ELEPHANT» in the room?

During the past two decades, the unequivocally recommended treatment method of Type 2 diabetes mellitus was insulin administration and intensification in the earliest possible stage of the diagnosis. This approach is not only unfounded but was never scientifically proven. Yet, it has been zealously...

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Autores principales:	Shmuel Levit, Shmuel Giveon, Yury I. Philippov, Ivan Panchev Domuschiev, Amir Zivony
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2016
Materias:	diabetes type 2 gravicentric energy-wasting energy-sparing calorie insulin intensification de-intensification algorithm cardiovascular cancer body mass index Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/4f28a807bb1f4ba0a7dd7c07b01656d6
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spelling	oai:doaj.org-article:4f28a807bb1f4ba0a7dd7c07b01656d62021-11-14T09:00:20ZType 2 diabetes therapeutic strategies: why don't we see the «ELEPHANT» in the room?2072-03512072-037810.14341/DM7077https://doaj.org/article/4f28a807bb1f4ba0a7dd7c07b01656d62016-11-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/7077https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378During the past two decades, the unequivocally recommended treatment method of Type 2 diabetes mellitus was insulin administration and intensification in the earliest possible stage of the diagnosis. This approach is not only unfounded but was never scientifically proven. Yet, it has been zealously advocated to medical professionals. In fact, a sound body of evidence disproves this long-standing treatment approach. This method is a cornerstone of, what we now know to be two great illusions of past century, namely, glucocentrism and intensification. Numerous recently published studies provide alarming data regarding serious side effects of blind intensification and insulin overdosing in T2DM. They raise major concerns and call for revision of the traditional approach. Since insulin is an integral and deeply rooted part of the intensification agenda of treating T2DM, it has now suffered a serious drawback. Alternatively, in this review authors present the novel Gravicentric (Energy) concept of T2DM acceptance and therapy. They offer a new classification of anti-diabetes drugs based on their energy effect and present their Gravicentric Algorithm for wide practical utilization. For that reason, the "ELEPHANT" abbreviation was found as a helpful reminder. Viewing T2DM as disease of energy balance together with anti – energy drugs implementation provide medical doctors an unique opportunity to transform T2DM from "slowly – progressive" disease to rapidly reversible condition, which it actually is.Shmuel LevitShmuel GiveonYury I. PhilippovIvan Panchev DomuschievAmir ZivonyEndocrinology Research Centrearticlediabetes type 2gravicentricenergy-wastingenergy-sparingcalorieinsulinintensificationde-intensificationalgorithmcardiovascularcancerbody mass indexNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 19, Iss 4, Pp 341-349 (2016)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	diabetes type 2 gravicentric energy-wasting energy-sparing calorie insulin intensification de-intensification algorithm cardiovascular cancer body mass index Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	diabetes type 2 gravicentric energy-wasting energy-sparing calorie insulin intensification de-intensification algorithm cardiovascular cancer body mass index Nutritional diseases. Deficiency diseases RC620-627 Shmuel Levit Shmuel Giveon Yury I. Philippov Ivan Panchev Domuschiev Amir Zivony Type 2 diabetes therapeutic strategies: why don't we see the «ELEPHANT» in the room?
description	During the past two decades, the unequivocally recommended treatment method of Type 2 diabetes mellitus was insulin administration and intensification in the earliest possible stage of the diagnosis. This approach is not only unfounded but was never scientifically proven. Yet, it has been zealously advocated to medical professionals. In fact, a sound body of evidence disproves this long-standing treatment approach. This method is a cornerstone of, what we now know to be two great illusions of past century, namely, glucocentrism and intensification. Numerous recently published studies provide alarming data regarding serious side effects of blind intensification and insulin overdosing in T2DM. They raise major concerns and call for revision of the traditional approach. Since insulin is an integral and deeply rooted part of the intensification agenda of treating T2DM, it has now suffered a serious drawback. Alternatively, in this review authors present the novel Gravicentric (Energy) concept of T2DM acceptance and therapy. They offer a new classification of anti-diabetes drugs based on their energy effect and present their Gravicentric Algorithm for wide practical utilization. For that reason, the "ELEPHANT" abbreviation was found as a helpful reminder. Viewing T2DM as disease of energy balance together with anti – energy drugs implementation provide medical doctors an unique opportunity to transform T2DM from "slowly – progressive" disease to rapidly reversible condition, which it actually is.
format	article
author	Shmuel Levit Shmuel Giveon Yury I. Philippov Ivan Panchev Domuschiev Amir Zivony
author_facet	Shmuel Levit Shmuel Giveon Yury I. Philippov Ivan Panchev Domuschiev Amir Zivony
author_sort	Shmuel Levit
title	Type 2 diabetes therapeutic strategies: why don't we see the «ELEPHANT» in the room?
title_short	Type 2 diabetes therapeutic strategies: why don't we see the «ELEPHANT» in the room?
title_full	Type 2 diabetes therapeutic strategies: why don't we see the «ELEPHANT» in the room?
title_fullStr	Type 2 diabetes therapeutic strategies: why don't we see the «ELEPHANT» in the room?
title_full_unstemmed	Type 2 diabetes therapeutic strategies: why don't we see the «ELEPHANT» in the room?
title_sort	type 2 diabetes therapeutic strategies: why don't we see the «elephant» in the room?
publisher	Endocrinology Research Centre
publishDate	2016
url	https://doaj.org/article/4f28a807bb1f4ba0a7dd7c07b01656d6
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Type 2 diabetes therapeutic strategies: why don't we see the «ELEPHANT» in the room?

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