Candidate silencer elements for the human and mouse genomes

Identification of silencer elements by computational or experimental approaches in a genome-wide manner is still challenging. Here authors define uncharacterized cis-regulatory elements (CREs) in human and mouse genomes likely containing silencer elements, and test them in cells using massively para...

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Autores principales:	Naresh Doni Jayavelu, Ajay Jajodia, Arpit Mishra, R. David Hawkins
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4f3605d087a948f498561d56217e2e9a
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spelling	oai:doaj.org-article:4f3605d087a948f498561d56217e2e9a2021-12-02T16:49:30ZCandidate silencer elements for the human and mouse genomes10.1038/s41467-020-14853-52041-1723https://doaj.org/article/4f3605d087a948f498561d56217e2e9a2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14853-5https://doaj.org/toc/2041-1723Identification of silencer elements by computational or experimental approaches in a genome-wide manner is still challenging. Here authors define uncharacterized cis-regulatory elements (CREs) in human and mouse genomes likely containing silencer elements, and test them in cells using massively parallel reporter assays to identify silencer elements that showed silencer activity.Naresh Doni JayaveluAjay JajodiaArpit MishraR. David HawkinsNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Naresh Doni Jayavelu Ajay Jajodia Arpit Mishra R. David Hawkins Candidate silencer elements for the human and mouse genomes
description	Identification of silencer elements by computational or experimental approaches in a genome-wide manner is still challenging. Here authors define uncharacterized cis-regulatory elements (CREs) in human and mouse genomes likely containing silencer elements, and test them in cells using massively parallel reporter assays to identify silencer elements that showed silencer activity.
format	article
author	Naresh Doni Jayavelu Ajay Jajodia Arpit Mishra R. David Hawkins
author_facet	Naresh Doni Jayavelu Ajay Jajodia Arpit Mishra R. David Hawkins
author_sort	Naresh Doni Jayavelu
title	Candidate silencer elements for the human and mouse genomes
title_short	Candidate silencer elements for the human and mouse genomes
title_full	Candidate silencer elements for the human and mouse genomes
title_fullStr	Candidate silencer elements for the human and mouse genomes
title_full_unstemmed	Candidate silencer elements for the human and mouse genomes
title_sort	candidate silencer elements for the human and mouse genomes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4f3605d087a948f498561d56217e2e9a
work_keys_str_mv	AT nareshdonijayavelu candidatesilencerelementsforthehumanandmousegenomes AT ajayjajodia candidatesilencerelementsforthehumanandmousegenomes AT arpitmishra candidatesilencerelementsforthehumanandmousegenomes AT rdavidhawkins candidatesilencerelementsforthehumanandmousegenomes
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Candidate silencer elements for the human and mouse genomes

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