New approaches for the management of bipolar disorder: role of sublingual asenapine in the treatment of mania

Calvert G Warren,1 Steven L Dubovsky1,21Department of Psychiatry, State University of New York at Buffalo, Buffalo, NY, USA; 2Departments of Psychiatry and Medicine, University of Colorado, Boulder, CO, USAAbstract: Bipolar disorder is a prevalent disorder that tends to become progressive without tr...

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Autores principales:	Warren CG, Dubovsky SL
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/4f36abf5fd7d47ea87933ddaa0bcdec3
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spelling	oai:doaj.org-article:4f36abf5fd7d47ea87933ddaa0bcdec32021-12-02T00:49:53ZNew approaches for the management of bipolar disorder: role of sublingual asenapine in the treatment of mania1176-63281178-2021https://doaj.org/article/4f36abf5fd7d47ea87933ddaa0bcdec32013-05-01T00:00:00Zhttp://www.dovepress.com/new-approaches-for-the-management-of-bipolar-disorder-role-of-sublingu-a13134https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Calvert G Warren,1 Steven L Dubovsky1,21Department of Psychiatry, State University of New York at Buffalo, Buffalo, NY, USA; 2Departments of Psychiatry and Medicine, University of Colorado, Boulder, CO, USAAbstract: Bipolar disorder is a prevalent disorder that tends to become progressive without treatment and with inadequate treatment. Second generation (atypical) antipsychotic drugs have increasingly been used as adjunctive treatment or monotherapy for mania, but they have the potential for significant adverse effects and their role in maintenance treatment remains unclear. Asenapine is a new atypical antipsychotic medication formulated in a sublingual preparation that has been studied for mania but not maintenance therapy. Evidence indicating efficacy, adverse effects, and potential benefits and drawbacks of using asenapine in the treatment of bipolar disorder based on currently available published data are summarized.Keywords: bipolar disorder, antipsychotic drug, mania, maintenance, sublingualWarren CGDubovsky SLDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 753-758 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Warren CG Dubovsky SL New approaches for the management of bipolar disorder: role of sublingual asenapine in the treatment of mania
description	Calvert G Warren,1 Steven L Dubovsky1,21Department of Psychiatry, State University of New York at Buffalo, Buffalo, NY, USA; 2Departments of Psychiatry and Medicine, University of Colorado, Boulder, CO, USAAbstract: Bipolar disorder is a prevalent disorder that tends to become progressive without treatment and with inadequate treatment. Second generation (atypical) antipsychotic drugs have increasingly been used as adjunctive treatment or monotherapy for mania, but they have the potential for significant adverse effects and their role in maintenance treatment remains unclear. Asenapine is a new atypical antipsychotic medication formulated in a sublingual preparation that has been studied for mania but not maintenance therapy. Evidence indicating efficacy, adverse effects, and potential benefits and drawbacks of using asenapine in the treatment of bipolar disorder based on currently available published data are summarized.Keywords: bipolar disorder, antipsychotic drug, mania, maintenance, sublingual
format	article
author	Warren CG Dubovsky SL
author_facet	Warren CG Dubovsky SL
author_sort	Warren CG
title	New approaches for the management of bipolar disorder: role of sublingual asenapine in the treatment of mania
title_short	New approaches for the management of bipolar disorder: role of sublingual asenapine in the treatment of mania
title_full	New approaches for the management of bipolar disorder: role of sublingual asenapine in the treatment of mania
title_fullStr	New approaches for the management of bipolar disorder: role of sublingual asenapine in the treatment of mania
title_full_unstemmed	New approaches for the management of bipolar disorder: role of sublingual asenapine in the treatment of mania
title_sort	new approaches for the management of bipolar disorder: role of sublingual asenapine in the treatment of mania
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/4f36abf5fd7d47ea87933ddaa0bcdec3
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New approaches for the management of bipolar disorder: role of sublingual asenapine in the treatment of mania

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